| | |
每股
|
| |
合计
|
| ||||||
公开发行价
|
| | | $ | 90.00 | | | | | $ | 450,000,000 | | |
承保折扣(1)
|
| | | $ | 4.50 | | | | | $ | 22,500,000 | | |
未扣除费用的收益给我们
|
| | | $ | 85.50 | | | | | $ | 427,500,000 | | |
| 美国银行证券 | | |
Jefferies
|
| |
Evercore ISI
|
|
| | |
第
页
|
| |||
招股说明书摘要
|
| | | | 1 | | |
风险因素
|
| | | | 15 | | |
有关前瞻性陈述的告诫声明
|
| | | | 85 | | |
收益使用情况
|
| | | | 87 | | |
股利政策
|
| | | | 88 | | |
企业重组
|
| | | | 89 | | |
大写
|
| | | | 90 | | |
稀释
|
| | | | 91 | | |
选定的合并财务信息
|
| | | | 92 | | |
管理层对财务状况和经营成果的讨论和分析
|
| | | | 94 | | |
业务
|
| | | | 121 | | |
管理
|
| | | | 238 | | |
主要股东
|
| | | | 253 | | |
关联方交易
|
| | | | 255 | | |
股本及章程说明
|
| | | | 260 | | |
荷兰公司法与美国公司法比较
|
| | | | 269 | | |
符合未来出售条件的普通股
|
| | | | 282 | | |
征税
|
| | | | 284 | | |
承销
|
| | | | 300 | | |
产品费用
|
| | | | 307 | | |
法律事务
|
| | | | 308 | | |
专家
|
| | | | 308 | | |
判决执行
|
| | | | 308 | | |
在哪里可以找到更多信息
|
| | | | 309 | | |
财务报表索引
|
| | | | F-1 | | |
| | |
截至的年度
12月31日 |
| |
截至的9个月
09月30日 |
| ||||||||||||||||||
| | |
2018
|
| |
2019
|
| |
2019
|
| |
2020
|
| ||||||||||||
| | |
(单位为千欧元,不包括每股金额)
|
| |||||||||||||||||||||
| | | | | | | | | | | | | | |
(未审核)
|
| |||||||||
营业报表和全面收益(亏损)数据:
|
| | | | | | | | | | | | | | | | | | | | | | | | |
收入
|
| | | | 12,871 | | | | | | 17,416 | | | | | | 10,600 | | | | | | 42,830 | | |
销售成本
|
| | | | (17,744) | | | | | | (27,983) | | | | | | (18,872) | | | | | | (7,049) | | |
销售和分销费用
|
| | | | (1,085) | | | | | | (1,755) | | | | | | (485) | | | | | | (809) | | |
研发费用
|
| | | | (41,722) | | | | | | (43,242) | | | | | | (30,665) | | | | | | (76,337) | | |
一般和行政费用
|
| | | | (25,289) | | | | | | (48,969) | | | | | | (28,504) | | | | | | (33,147) | | |
其他营业收入
|
| | | | 808 | | | | | | 5,587 | | | | | | 3,838 | | | | | | 11,695 | | |
其他运营费用
|
| | | | (663) | | | | | | (552) | | | | | | (339) | | | | | | (357) | | |
营业亏损
|
| | | | (72,824) | | | | | | (99,498) | | | | | | (64,427) | | | | | | (63,174) | | |
财务收入
|
| | | | 1,968 | | | | | | 833 | | | | | | 3,133 | | | | | | 5,103 | | |
财务费用
|
| | | | (275) | | | | | | (1,460) | | | | | | (2,924) | | | | | | (14,519) | | |
所得税前亏损
|
| | | | (71,131) | | | | | | (100,125) | | | | | | (64,218) | | | | | | (72,590) | | |
所得税优惠(费用)
|
| | | | (110) | | | | | | 252 | | | | | | 335 | | | | | | 1,615 | | |
净亏损
|
| | | | (71,241) | | | | | | (99,873) | | | | | | (63,883) | | | | | | (70,975) | | |
其他综合损益: | | | | | | | | | | | | | | | | | | | | | | | | | |
随后可能重新分类为损益的项目
|
| | | | | | | | | | | | | | | | | | | | | | | | |
外币调整
|
| | | | 66 | | | | | | 32 | | | | | | (20) | | | | | | 76 | | |
全面亏损
|
| | | | (71,175) | | | | | | (99,841) | | | | | | (63,903) | | | | | | (70,899) | | |
|
| | |
截至2020年9月30日
|
| |||||||||
| | |
实际
|
| |
形式(1)(2)
|
| ||||||
| | |
(单位:千欧元)
(未审核) |
| |||||||||
财务状况数据报表: | | | | | | | | | | | | | |
现金和现金等价物
|
| | | | 892,399 | | | | | | 1,239,893 | | |
总资产
|
| | | | 1,021,907 | | | | | | 1,369,401 | | |
总负债
|
| | | | 260,557 | | | | | | 260,557 | | |
总股本
|
| | | | 761,350 | | | | | | 1,108,844 | | |
| | |
实际
|
| |
形式
|
| ||||||
| | |
(单位:千欧元)
(未审核) |
| |||||||||
现金和现金等价物
|
| | | | 892,399(1) | | | | | | 1,239,893 | | |
股权: | | | | | | | | | | | | | |
已发行资本
|
| | | | 21,560 | | | | | | 22,160 | | |
资本公积
|
| | | | 1,326,766 | | | | | | 1,673,660 | | |
累计亏损
|
| | | | (586,922) | | | | | | (586,922) | | |
其他综合收益
|
| | | | (54) | | | | | | (54) | | |
股东权益总额
|
| | | | 761,350 | | | | | | 1,108,844 | | |
总市值
|
| | |
|
761,350
|
| | | |
|
1,108,844
|
| |
| | |
$
|
| |
€
|
| ||||||
普通股每股公开发行价
|
| | | | 90.00 | | | | | | 73.34 | | |
截至2020年9月30日每股普通股的历史有形账面净值
|
| | | | 5.11 | | | | | | 4.16 | | |
可归因于此的每股普通股有形账面净值增加
提供服务 |
| | | | 2.16 | | | | | | 1.76 | | |
预计发售生效后,2020年9月30日普通股的每股有形账面净值
|
| | | | 7.27 | | | | | | 5.92 | | |
向新投资者摊薄每股普通股
|
| | | | 82.73 | | | | | | 67.42 | | |
新投资者每股普通股摊薄百分比
|
| | | | 91.9% | | | | | | 91.9% | | |
| | |
截至的年度
12月31日 |
| |
截至前九个月
09月30日 |
| ||||||||||||||||||
| | |
2018
|
| |
2019
|
| |
2019
|
| |
2020
|
| ||||||||||||
| | |
(单位为千欧元,不包括每股金额)
|
| |||||||||||||||||||||
| | | | | | | | | | | | | | |
(未审核)
|
| |||||||||
营业报表和全面收益(亏损)数据:
|
| | | | | | | | | | | | | | | | | | | | | | | | |
收入
|
| | | | 12,871 | | | | | | 17,416 | | | | | | 10,600 | | | | | | 42,830 | | |
销售成本
|
| | | | (17,744) | | | | | | (27,983) | | | | | | (18,872) | | | | | | (7,049) | | |
销售和分销费用
|
| | | | (1,085) | | | | | | (1,755) | | | | | | (485) | | | | | | (809) | | |
研发费用
|
| | | | (41,722) | | | | | | (43,242) | | | | | | (30,665) | | | | | | (76,337) | | |
一般和行政费用
|
| | | | (25,289) | | | | | | (48,969) | | | | | | (28,504) | | | | | | (33,147) | | |
其他营业收入
|
| | | | 808 | | | | | | 5,587 | | | | | | 3,838 | | | | | | 11,695 | | |
其他运营费用
|
| | | | (663) | | | | | | (552) | | | | | | (339) | | | | | | (357) | | |
营业亏损
|
| | | | (72,824) | | | | | | (99,498) | | | | | | (64,427) | | | | | | (63,174) | | |
财务收入
|
| | | | 1,968 | | | | | | 833 | | | | | | 3,133 | | | | | | 5,103 | | |
财务费用
|
| | | | (275) | | | | | | (1,460) | | | | | | (2,924) | | | | | | (14,519) | | |
所得税前亏损
|
| | | | (71,131) | | | | | | (100,125) | | | | | | (64,218) | | | | | | (72,590) | | |
所得税优惠(费用)
|
| | | | (110) | | | | | | 252 | | | | | | 335 | | | | | | 1,615 | | |
净亏损
|
| | | | (71,241) | | | | | | (99,873) | | | | | | (63,883) | | | | | | (70,975) | | |
其他综合损益: | | | | | | | | | | | | | | | | | | | | | | | | | |
随后可能重新分类为损益的项目
|
| | | | | | | | | | | | | | | | | | | | | | | | |
外币调整
|
| | | | 66 | | | | | | 32 | | | | | | (20) | | | | | | 76 | | |
全面亏损
|
| | | | (71,175) | | | | | | (99,841) | | | | | | (63,903) | | | | | | (70,899) | | |
|
| | |
截至12月31日
|
| |
截至
09月30日 |
| ||||||||||||
| | |
2018
|
| |
2019
|
| |
2020
|
| |||||||||
| | | | | | | | | | | | | | |
(未审核)
|
| |||
| | |
(单位:千欧元)
|
| |||||||||||||||
财务状况数据报表: | | | | | | | | | | | | | | | | | | | |
现金和现金等价物
|
| | | | 21,380 | | | | | | 30,684 | | | | | | 892,399 | | |
总资产
|
| | | | 125,659 | | | | | | 130,620 | | | | | | 1,021,907 | | |
总负债
|
| | | | 93,576 | | | | | | 173,422 | | | | | | 260,557 | | |
总股本
|
| | | | 32,083 | | | | | | (42,802) | | | | | | 761,350 | | |
| | |
截至的9个月
09月30日 |
| |||||||||
| | |
2019
|
| |
2020
|
| ||||||
| | |
(未审核)
|
| |||||||||
| | |
(单位:千欧元,
每股数据除外) |
| |||||||||
营业报表和全面收益(亏损)数据: | | | | | | | | | | | | | |
收入
|
| | | | 10,600 | | | | | | 42,830 | | |
销售成本
|
| | | | (18,872) | | | | | | (7,049) | | |
销售和分销费用
|
| | | | (485) | | | | | | (809) | | |
研发费用
|
| | | | (30,665) | | | | | | (76,337) | | |
一般和行政费用
|
| | | | (28,504) | | | | | | (33,147) | | |
其他营业收入
|
| | | | 3,838 | | | | | | 11,695 | | |
其他运营费用
|
| | | | (339) | | | | | | (357) | | |
营业亏损
|
| | | | (64,427) | | | | | | (63,174) | | |
财务收入
|
| | | | 3,133 | | | | | | 5,103 | | |
财务费用
|
| | | | (2,924) | | | | | | (14,519) | | |
所得税前亏损
|
| | | | (64,218) | | | | | | (72,590) | | |
所得税优惠(费用)
|
| | | | 335 | | | | | | 1,615 | | |
净亏损
|
| | | | (63,883) | | | | | | (70,975) | | |
其他综合损益: | | | | | | | | | | | | | |
随后可能重新分类为损益的项目
|
| | | | | | | | | | | | |
外币调整
|
| | | | (20) | | | | | | 76 | | |
全面亏损
|
| | | | (63,903) | | | | | | (70,899) | | |
每股净亏损(基本和稀释后)
|
| | | | (0.66) | | | | | | (0.61) | | |
| | |
截至的9个月
09月30日 |
| |||||||||
| | |
2019
|
| |
2020
|
| ||||||
| | |
(单位:千欧元)
(未审核) |
| |||||||||
人员
|
| | | | (7,249) | | | | | | (2,171) | | |
材料
|
| | | | (4,022) | | | | | | (1,380) | | |
第三方服务
|
| | | | (5,339) | | | | | | (2,432) | | |
维护和租赁
|
| | | | (770) | | | | | | (752) | | |
摊销折旧
|
| | | | (1,259) | | | | | | (250) | | |
其他
|
| | | | (233) | | | | | | (64) | | |
合计 | | | | | (18,872) | | | | | | (7,049) | | |
| | |
截至的9个月
09月30日 |
| |||||||||
| | |
2019
|
| |
2020
|
| ||||||
| | |
(单位:千欧元)
(未审核) |
| |||||||||
人员
|
| | | | (257) | | | | | | (755) | | |
摊销折旧
|
| | | | (61) | | | | | | (77) | | |
其他
|
| | | | (167) | | | | | | 23 | | |
合计 | | | | | (485) | | | | | | (809) | | |
| | |
截至的9个月
09月30日 |
| |||||||||
| | |
2019
|
| |
2020
|
| ||||||
| | |
(单位:千欧元)
(未审核) |
| |||||||||
材料
|
| | | | (2,605) | | | | | | (21,595) | | |
人员
|
| | | | (9,321) | | | | | | (16,213) | | |
摊销折旧
|
| | | | (895) | | | | | | (2,589) | | |
注册合法权利的专利和费用
|
| | | | (3,143) | | | | | | (3,525) | | |
第三方服务
|
| | | | (14,426) | | | | | | (27,973) | | |
维护和租赁
|
| | | | (20) | | | | | | (560) | | |
其他
|
| | | | (255) | | | | | | (3,882) | | |
合计 | | | | | (30,665) | | | | | | (76,337) | | |
| | |
截至的9个月
09月30日 |
| |||||||||
| | |
2019
|
| |
2020
|
| ||||||
| | |
(单位:千欧元)
(未审核) |
| |||||||||
关键程序(CV8102、CV7202和CVnCoV) | | | | | | | | | | | | | |
CV8102
|
| | | | 3,871 | | | | | | 5,443 | | |
CV7202
|
| | | | 1,374 | | | | | | 4,474 | | |
CVnCoV
|
| | | | — | | | | | | 27,504 | | |
其他研发项目
|
| | | | 10,126 | | | | | | 9,050 | | |
未分配成本(1)
|
| | | | 15,294 | | | | | | 30,864 | | |
合计 | | | | | 30,665 | | | | | | 76,337 | | |
| | |
截至的9个月
09月30日 |
| |||||||||
| | |
2019
|
| |
2020
|
| ||||||
| | |
(单位:千欧元)
(未审核) |
| |||||||||
人员
|
| | | | (16,747) | | | | | | (15,847) | | |
维护和租赁成本
|
| | | | (2,138) | | | | | | (1,571) | | |
第三方服务
|
| | | | (4,203) | | | | | | (5,097) | | |
法律和其他专业服务
|
| | | | (825) | | | | | | (2,276) | | |
摊销折旧
|
| | | | (2,709) | | | | | | (4,382) | | |
其他
|
| | | | (1,882) | | | | | | (3,974) | | |
合计 | | | | | (28,504) | | | | | | (33,147) | | |
| | |
截至的年度
12月31日 |
| |||||||||
| | |
2018
|
| |
2019
|
| ||||||
| | |
(单位为千欧元,
除外
每股数据) |
| |||||||||
营业报表和全面收益(亏损)数据: | | | | | | | | | | | | | |
收入
|
| | | | 12,871 | | | | | | 17,416 | | |
销售成本
|
| | | | (17,744) | | | | | | (27,983) | | |
销售和分销费用
|
| | | | (1,085) | | | | | | (1,755) | | |
研发费用
|
| | | | (41,722) | | | | | | (43,242) | | |
一般和行政费用
|
| | | | (25,289) | | | | | | (48,969) | | |
其他营业收入
|
| | | | 808 | | | | | | 5,587 | | |
其他运营费用
|
| | | | (663) | | | | | | (552) | | |
营业亏损
|
| | | | (72,824) | | | | | | (99,498) | | |
财务收入
|
| | | | 1,968 | | | | | | 833 | | |
财务费用
|
| | | | (275) | | | | | | (1,460) | | |
所得税前亏损
|
| | | | (71,131) | | | | | | (100,125) | | |
所得税优惠(费用)
|
| | | | (110) | | | | | | 252 | | |
本年度净亏损
|
| | | | (71,241) | | | | | | (99,873) | | |
其他综合损益: | | | | | | | | | | | | | |
随后可能重新分类为损益的项目
|
| | | | | | | | | | | | |
外币调整
|
| | | | 66 | | | | | | 32 | | |
本年度综合亏损总额
|
| | | | (71,175) | | | | | | (99,841) | | |
每股净亏损(基本和稀释后)
|
| | | | (0.74) | | | | | | (1.03) | | |
| | |
截至的年度
12月31日 |
| |||||||||
| | |
2018
|
| |
2019
|
| ||||||
| | |
(单位:千欧元)
|
| |||||||||
人员
|
| | | | (7,703) | | | | | | (9,855) | | |
材料
|
| | | | (4,941) | | | | | | (7,542) | | |
第三方服务
|
| | | | (2,340) | | | | | | (7,268) | | |
维护和租赁
|
| | | | (1,758) | | | | | | (1,060) | | |
摊销折旧
|
| | | | (893) | | | | | | (2,038) | | |
其他
|
| | | | (109) | | | | | | (220) | | |
合计 | | | | | (17,744) | | | | | | (27,983) | | |
| | |
截至的年度
12月31日 |
| |||||||||
| | |
2018
|
| |
2019
|
| ||||||
| | |
(单位:千欧元)
|
| |||||||||
人员
|
| | | | (581) | | | | | | (1,263) | | |
维护和租赁成本
|
| | | | (300) | | | | | | (167) | | |
摊销折旧
|
| | | | (95) | | | | | | (81) | | |
其他
|
| | | | (109) | | | | | | (243) | | |
合计 | | | | | (1,085) | | | | | | (1,755) | | |
| | |
截至的年度
12月31日 |
| |||||||||
| | |
2018
|
| |
2019
|
| ||||||
| | |
(单位:千欧元)
|
| |||||||||
材料
|
| | | | (5,867) | | | | | | (4,015) | | |
人员
|
| | | | (7,565) | | | | | | (14,385) | | |
摊销折旧
|
| | | | (1,143) | | | | | | (474) | | |
注册合法权利的专利和费用
|
| | | | (4,847) | | | | | | (4,551) | | |
第三方服务
|
| | | | (19,921) | | | | | | (18,626) | | |
维护和租赁
|
| | | | (1,156) | | | | | | (670) | | |
其他
|
| | | | (1,223) | | | | | | (521) | | |
合计 | | | | | (41,722) | | | | | | (43,242) | | |
| | |
截至的年度
12月31日 |
| |||||||||
| | |
2018
|
| |
2019
|
| ||||||
| | |
(单位:千欧元)
|
| |||||||||
关键程序(CV8102和CV7202) | | | | | | | | | | | | | |
CV8102
|
| | | | (1,525) | | | | | | (4,511) | | |
CV7202
|
| | | | (1,987) | | | | | | (2,236) | | |
其他研发项目
|
| | | | (14,047) | | | | | | (14,271) | | |
未分配成本(1)
|
| | | | (24,163) | | | | | | (22,224) | | |
合计 | | | | | (41,722) | | | | | | (43,242) | | |
| | |
截至的年度
12月31日 |
| |||||||||
| | |
2018
|
| |
2019
|
| ||||||
| | |
(单位:千欧元)
|
| |||||||||
人员
|
| | | | (10,084) | | | | | | (31,645) | | |
维护和租赁成本
|
| | | | (3,239) | | | | | | (4,604) | | |
第三方服务
|
| | | | (4,006) | | | | | | (5,970) | | |
法律和其他专业服务
|
| | | | (4,078) | | | | | | (2,110) | | |
摊销折旧
|
| | | | (1,635) | | | | | | (2,182) | | |
其他
|
| | | | (2,247) | | | | | | (2,458) | | |
合计 | | | | | (25,289) | | | | | | (48,969) | | |
| | |
截至的9个月
09月30日 |
| |||||||||
| | |
2019
|
| |
2020
|
| ||||||
| | |
(单位:千欧元)
(未审核) |
| |||||||||
净现金流来源(用于): | | | | | | | | | | | | | |
经营活动
|
| | | | (67,979) | | | | | | 80,982 | | |
投资活动
|
| | | | 33,047 | | | | | | (17,466) | | |
融资活动
|
| | | | 48,669 | | | | | | 794,350 | | |
货币换算收益对现金和现金等价物的影响
|
| | | | (139) | | | | | | 3,849 | | |
整体现金流入
|
| | | | 13,598 | | | | | | 861,715 | | |
| | |
截至的年度
12月31日 |
| |||||||||
| | |
2018
|
| |
2019
|
| ||||||
| | |
(单位:千欧元)
|
| |||||||||
净现金流来源(用于): | | | | | | | | | | | | | |
经营活动
|
| | | | (74,110) | | | | | | (86,963) | | |
投资活动
|
| | | | (4,264) | | | | | | 28,181 | | |
融资活动
|
| | | | (112) | | | | | | 67,979 | | |
货币换算收益对现金和现金等价物的影响
|
| | | | 213 | | | | | | 107 | | |
整体现金流入(流出)
|
| | | | (78,273) | | | | | | 9,304 | | |
| | |
按期付款
|
| |||||||||||||||||||||||||||||||||||||||
| | |
总计(2)
|
| |
2021
|
| |
2022
|
| |
2023
|
| |
2024
|
| |
2025
|
| |
此后
|
| |||||||||||||||||||||
| | |
(单位:千欧元)
|
| |||||||||||||||||||||||||||||||||||||||
合同CMO承诺(1)
|
| | | | 97,151 | | | | | | 97,151 | | | | | | — | | | | | | — | | | | | | — | | | | | | — | | | | | | — | | |
租赁负债
|
| | | | 30,087 | | | | | | 2,961 | | | | | | 3,074 | | | | | | 3,131 | | | | | | 3,310 | | | | | | 3,449 | | | | | | 14,161 | | |
长期债务义务
|
| | | | 25,875 | | | | | | — | | | | | | — | | | | | | — | | | | | | — | | | | | | — | | | | | | 25,875 | | |
合计 | | | | | 153,112 | | | | | | 100,112 | | | | | | 3,074 | | | | | | 3,131 | | | | | | 3,310 | | | | | | 3,449 | | | | | | 30,086 | | |
至少发生一次事件的患者,n(%)
|
| |
地层1
(n=16) |
| |
第2层
(n=8) |
| |
第三层
(n=2) |
| |
总体
(n=26) |
| ||||||||||||
TEAE
|
| | | | 16 (100.0) | | | | | | 8 (100.0) | | | | | | 2 (100.0) | | | | | | 26 (100.0) | | |
BI1361849和/或与辐射相关的AE
|
| | | | 16 (100.0) | | | | | | 8(100.0) | | | | | | 2(100.0) | | | | | | 26(100.0) | | |
与BI1361849相关的TEAE
|
| | | | 15(93.8) | | | | | | 8(100.0) | | | | | | 2(100.0) | | | | | | 26(96.2) | | |
与辐射相关的TEAE
|
| | | | 4(25.0) | | | | | | 1(12.5) | | | | | | 0(50.0) | | | | | | 5(19.2) | | |
严重的TEAE
|
| | | | 7(43.8) | | | | | | 3(37.5) | | | | | | 1(50.0) | | | | | | 11(42.3) | | |
严重的BI1361849和/或与辐射相关的AE
|
| | | | 1(6.3) | | | | | | 0 | | | | | | 0 | | | | | | 1(3.8) | | |
与BI1361849相关
|
| | | | 0 | | | | | | 0 | | | | | | 0 | | | | | | 0 | | |
与辐射相关的
|
| | | | 1(6.3) | | | | | | 0 | | | | | | 0 | | | | | | 1(3.8) | | |
TEAE毒性等级≥3(A)
|
| | | | 9(56.3) | | | | | | 4(50.0) | | | | | | 2(100.0) | | | | | | 15(57.7) | | |
BI1361849和/或与辐射相关的AE毒性等级≥3(A)
|
| | | | 2(12.5) | | | | | | 1(12.5) | | | | | | 1(50.0) | | | | | | 4(15.4) | | |
与BI1361849相关
|
| | | | 1(6.3) | | | | | | 1(12.5) | | | | | | 1(50.0) | | | | | | 3(11.5) | | |
与辐射相关的
|
| | | | 1(6.3) | | | | | | 0 | | | | | | 0 | | | | | | 1(3.8) | | |
严重的BI1361849和/或与辐射相关的AE毒性等级为≥3(A)
|
| | | | 1(6.3) | | | | | | 0 | | | | | | 0 | | | | | | 1(3.8) | | |
与BI1361849相关
|
| | | | 0 | | | | | | 0 | | | | | | 0 | | | | | | 0 | | |
与辐射相关的
|
| | | | 1(6.3) | | | | | | 0 | | | | | | 0 | | | | | | 1(3.8) | | |
TEAE导致停产
|
| | | | 4(25.0) | | | | | | 0 | | | | | | 0 | | | | | | 4(15.4) | | |
TEAE毒性等级为≥3,导致停产
|
| | | | 2(12.5) | | | | | | 0 | | | | | | 0 | | | | | | 2(7.7) | | |
TEAE导致中断/剂量修改
|
| | | | 4(25.0) | | | | | | 0 | | | | | | 0 | | | | | | 4(15.4) | | |
TEAE导致死亡
|
| | | | 0 | | | | | | 0 | | | | | | 0 | | | | | | 0 | | |
| | |
个有反应的患者,n(%)[95%置信区间]
|
| |||||||||
参数
|
| |
地层1
(n=16) |
| |
第2层
(n=8) |
| |
第三层
(n=2) |
| |
总体
(n=26) |
|
回复(CR+PR)率
|
| |
1 (6.3)
|
| |
0
|
| |
0
|
| |
1 (3.8)
|
|
| | |
[0.2-30.2]
|
| |
[0.0-36.9]
|
| |
[0.0-84.2]
|
| |
[0.1-19.6]
|
|
最佳总体反应 | | | | | | | | | | | | | |
CR
|
| |
0
|
| |
0
|
| |
0
|
| |
0
|
|
| | |
[0.0-20.6]
|
| |
[0.0-36.9]
|
| |
[0.0-84.2]
|
| |
[0.0-13.2]
|
|
公关
|
| |
1 (6.3)
|
| |
0
|
| |
0
|
| |
1 (3.8)
|
|
| | |
[0.2-30.2]
|
| |
[0.0-36.9]
|
| |
[0.0-84.2]
|
| |
[0.1-19.6]
|
|
标清
|
| |
8 (50.0)
|
| |
3 (37.5)
|
| |
1 (50.0)
|
| |
12 (46.2)
|
|
| | |
[24.7-75.3]
|
| |
[8.5-75.5]
|
| |
[1.3-98.7]
|
| |
[26.6-66.6]
|
|
PD
|
| |
7 (43.8)
|
| |
4 (50.0)
|
| |
1(50.0)
|
| |
12 (46.2)
|
|
| | |
[19.8-70.1]
|
| |
[15.7-84.3]
|
| |
[1.3-98.7]
|
| |
[26.6-66.6]
|
|
东北
|
| |
0
|
| |
1 (12.5)
|
| |
0
|
| |
1 (3.8)
|
|
| | |
[0.0-20.6]
|
| |
[0.3-52.7]
|
| |
[0.0-84.2]
|
| |
[0.1-19.6]
|
|
位置
|
| |
区域
(近似平方英尺) |
| |||
德国: | | | | | | | |
Tübingen
|
| | | | 189,000 | | |
美因河畔法兰克福
|
| | | | 8,600 | | |
合计
|
| | | | 197,600 | | |
美国: | | | | | | | |
波士顿
|
| | | | 12,900 | | |
合计
|
| | | | 12,900 | | |
合计
|
| | | | 210,500 | | |
名称
|
| |
年龄
|
| |
服刑
|
| |
哪一年
期限到期 |
| |
职位
|
|
Franz-Werner Haas,LLD,LLM | | | 51 | | |
2020年6月 - 颁奖典礼
|
| | 2022 | | | 首席执行官 | |
弗洛里安·冯德穆尔贝,博士,MBA
|
| | 48 | | |
2015年9月 - 展示
|
| | 2023 | | | 首席生产官 | |
Mariola Fotin-Mleczek博士 | | | 53 | | |
2015年9月 - 展示
|
| | 2023 | | | 首席技术官 | |
皮埃尔·科米拉,B.Sc. | | | 47 | | |
2016年11月11日 - 展示
|
| | 2021 | | | 首席财务官 | |
安东尼·布兰克博士(1) | | | 52 | | |
2020年12月 - 颁奖典礼
|
| | 2023 | | |
首席商务官/
首席商务官
|
|
Bernd Winterhalter医学博士(2) | | | 62 | | |
2018年6月 - 展示
|
| | 未定义 | | |
首席开发官
(临时)
|
|
Igor Splawski,博士,硕士 | | | 52 | | |
2020年7月 - 展示
|
| | 2023 | | | 首席科学官 | |
名称
|
| |
年龄
|
| |
服刑
|
| |
年(
)
哪个 术语 过期 |
| |
函数
|
|
Jean Stéphenne男爵,理学硕士,MBA | | |
71
|
| |
2015年8月 - 展示
|
| |
2024
|
| |
董事长兼监事
导演 |
|
拉尔夫·克莱门斯医学博士 | | |
68
|
| |
2015年8月 - 展示
|
| |
2024
|
| | 监事长 | |
Mathias Hothum博士 | | |
53
|
| |
2015年8月 - 展示
|
| |
2024
|
| | 监事长 | |
汉斯·克里斯托夫·坦纳(Hans Christoph Tanner)博士 | | |
69
|
| |
2015年8月 - 展示
|
| |
2024
|
| | 监事长 | |
Friedrich von Bohlen und Halbach博士 | | |
58
|
| |
2015年8月 - 展示
|
| |
2022
|
| |
副董事长兼监事
导演
|
|
医学博士蒂莫西·M·赖特 | | |
65
|
| |
2019年6月 - 展示
|
| |
2022
|
| | 监事长 | |
克雷格·A·图曼(Craig A.Tooman),MBA | | |
55
|
| |
2019年6月 - 展示
|
| |
2022
|
| | 监事长 | |
Viola Bronsema博士 | | |
57
|
| |
2020年8月 - 展示
|
| |
2024
|
| | 监事长 | |
名称
|
| |
已修复
薪酬 (€) |
| |
出席人数
费用 (€) |
| |
合计
薪酬 (€) |
| |||||||||
让·斯特芬男爵
|
| | | | 102,747 | | | | | | — | | | | | | 102,747 | | |
拉尔夫·克莱门斯
|
| | | | 55,000 | | | | | | 27,500 | | | | | | 82,500 | | |
Mathias Hothum
|
| | | | 55,000 | | | | | | 27,500 | | | | | | 82,500 | | |
汉斯·克里斯托夫·坦纳
|
| | | | 55,000 | | | | | | 27,500 | | | | | | 82,500 | | |
Friedrich von Bohlen und Halbach
|
| | | | 55,000 | | | | | | — | | | | | | 55,000 | | |
英格玛·霍尔(1)
|
| | | | 21,301 | | | | | | — | | | | | | 21,301 | | |
蒂莫西·M·赖特
|
| | | | 55,000 | | | | | | — | | | | | | 55,000 | | |
克雷格·A·图曼
|
| | | | 55,000 | | | | | | — | | | | | | 55,000 | | |
Viola Bronsema博士(2)
|
| | | | 20,644 | | | | | | — | | | | | | 20,644 | | |
名称
|
| |
数量
个共享 |
| |
百分比
共 个共享 出色的 |
| |
投票
权利 |
| |||||||||
让·斯特芬男爵
|
| | | | — | | | | | | — | | | | | | — | | |
拉尔夫·克莱门斯
|
| | | | — | | | | | | — | | | | | | — | | |
Mathias Hothum
|
| | | | — | | | | | | — | | | | | | — | | |
汉斯·克里斯托夫·坦纳
|
| | | | 188,172 | | | | | | 0.1% | | | | | | — | | |
Friedrich von Bohlen und Halbach
|
| | | | 241,935 | | | | | | 0.1% | | | | | | — | | |
英格玛·霍尔(1)
|
| | | | 1,129,165 | | | | | | 0.63% | | | | | | — | | |
蒂莫西·M·赖特
|
| | | | — | | | | | | — | | | | | | — | | |
克雷格·A·图曼
|
| | | | — | | | | | | — | | | | | | — | | |
Viola Bronsema博士(2)
|
| | | | — | | | | | | — | | | | | | — | | |
名称
|
| |
号码
共 个 个 选项 |
| |
标题
|
| |
金额
共 个 个 证券 (€) |
| |
练习
价格 (€) |
| |
购买
价格 (€) |
| |
过期日期
|
| |||||||||||||||
让·斯特芬男爵
|
| | | | — | | | |
—
|
| | | | — | | | | | | — | | | | | | — | | | | | | — | | |
拉尔夫·克莱门斯
|
| | | | — | | | |
—
|
| | | | — | | | | | | — | | | | | | — | | | | | | — | | |
Mathias Hothum
|
| | | | — | | | |
—
|
| | | | — | | | | | | — | | | | | | — | | | | | | — | | |
汉斯·克里斯托夫·坦纳
|
| | | | — | | | |
—
|
| | | | — | | | | | | — | | | | | | — | | | | | | — | | |
Friedrich von Bohlen und Halbach
|
| | | | — | | | |
—
|
| | | | — | | | | | | — | | | | | | — | | | | | | — | | |
英格玛·霍尔(1)
|
| | | | 369,423 | | | |
股票期权
奖项 |
| | | | 2,776 | | | | | | 0.01 | | | | | | 2,776 | | | | | | 12/31/2021 | | |
蒂莫西·M·赖特
|
| | | | — | | | |
—
|
| | | | — | | | | | | — | | | | | | — | | | | | | — | | |
克雷格·A·图曼
|
| | | | — | | | |
—
|
| | | | — | | | | | | — | | | | | | — | | | | | | — | | |
Viola Bronsema博士(2)
|
| | | | — | | | |
—
|
| | | | — | | | | | | — | | | | | | — | | | | | | — | | |
名称*
|
| |
工资
(€) |
| |
奖金(1)
(€) |
| |
所有其他
薪酬(2) (€) |
| |
合计
薪酬(3) (€) |
| ||||||||||||
Daniel L.Menichella(4)(5)
|
| | | | 129,843 | | | | | | 318,218 | | | | | | 651,025(6) | | | | | | 1,099,086 | | |
Florian von der Mulbe
|
| | | | 258,533 | | | | | | 235,375 | | | | | | 25,482 | | | | | | 519,390 | | |
Mariola Fotin-Mleczek
|
| | | | 226,866 | | | | | | 221,875 | | | | | | 19,492 | | | | | | 468,233 | | |
弗朗茨-维尔纳·哈斯
|
| | | | 264,866 | | | | | | 312,150 | | | | | | 24,865 | | | | | | 601,881 | | |
皮埃尔·科穆拉
|
| | | | 250,199 | | | | | | 235,375 | | | | | | 99,928 | | | | | | 585,502 | | |
Bernd Winterhalter(7)
|
| | | | 455,955 | | | | | | — | | | | | | — | | | | | | 455,955 | | |
Dimitris Voliotis(8)(9)
|
| | | | 11,283 | | | | | | — | | | | | | 306,935 | | | | | | 318,218 | | |
Igor Splawski(10)(11)
|
| | | | 146,883 | | | | | | — | | | | | | 74,154 | | | | | | 220,037 | | |
名称*
|
| |
数量
个共享 |
| |
百分比
共 个共享 出色的 |
| |
投票
权利 |
| |||||||||
Daniel L.Menichella(1)
|
| | | | — | | | | | | — | | | | | | — | | |
Florian von der Mulbe
|
| | | | 820,025 | | | | | | 0.45% | | | | | | — | | |
Mariola Fotin-Mleczek
|
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弗朗茨-维尔纳·哈斯
|
| | | | — | | | | | | — | | | | | | — | | |
名称*
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数量
个共享 |
| |
百分比
共 个共享 出色的 |
| |
投票
权利 |
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皮埃尔·科穆拉
|
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Bernd Winterhalter(2)
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迪米特里斯·沃利奥蒂斯
|
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Igor Splawski(3)
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名称*
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数量
选项 |
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标题
|
| |
金额
共 个 个 证券 (€) |
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练习
价格 (€) |
| |
购买
价格 (€) |
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过期
日期 |
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Daniel Menichella(1)
|
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—
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| | | | — | | | |
—
|
| |
—
|
| | | | — | | |
Florian von der Mulbe
|
| | | | 268,417 | | | |
股票期权奖励
|
| | | | 2,017 | | | |
0.01
|
| |
2,017
|
| | | | 12/31/2021 | | |
Mariola Fotin-Mleczek
|
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—
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—
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—
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弗朗茨-维尔纳·哈斯
|
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—
|
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—
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—
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皮埃尔·科穆拉
|
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—
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—
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—
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Bernd Winterhalter(2)
|
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—
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—
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—
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迪米特里斯·沃利奥蒂斯
|
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—
|
| | | | — | | | |
—
|
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—
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| | | | — | | |
Igor Splawski(3)(4)
|
| | | | 266,155 | | | |
LTIP选项奖
|
| | | | 266,155 | | | |
10.04
|
| |
—
|
| | | | 7/14/2030 | | |
名称
|
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计划
|
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vs
分 已批准 |
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最大
归属 分 |
| |
从
开始
归属 期间 (仅限 用于新 参与者) |
| |
授予日期
(日期: 分配 Letter) |
| |
归属
期间 |
| |
VSOP
计划 |
| |
有效
至 |
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Florian von der Mulbe
|
| | | | vS | | | | | | 103,534 | | | | | | 103,534 | | | | | | | | | | | | 01.01.2009 | | | | | | 36 | | | |
之前的VSOP
|
| | | | 31.12.2025 | | |
Florian von der Mulbe
|
| | | | vS | | | | | | 463,908 | | | | | | 463,908 | | | | | | | | | | | | 01.01.2011 | | | | | | 36 | | | |
之前的VSOP
|
| | | | 31.12.2025 | | |
Florian von der Mulbe
|
| | | | vS | | | | | | 97,944 | | | | | | 97,944 | | | | | | | | | | | | 01.01.2013 | | | | | | 36 | | | |
之前的VSOP
|
| | | | 31.12.2025 | | |
Florian von der Mulbe
|
| | | | vS | | | | | | 202,543 | | | | | | 202,543 | | | | | | | | | | | | 01.01.2015 | | | | | | 12 | | | |
之前的VSOP
|
| | | | 31.12.2025 | | |
Florian von der Mulbe
|
| | | | vS | | | | | | 811,774 | | | | | | 811,774 | | | | | | | | | | | | 11.12.2015 | | | | | | 12 | | | |
之前的VSOP
仅限IPO
|
| | | | 31.12.2025 | | |
Mariola Fotin-Mleczek
|
| | | | vS | | | | | | 42,051 | | | | | | 42,051 | | | | | | | | | | | | 01.01.2009 | | | | | | 60 | | | |
之前的VSOP
|
| | | | 31.12.2025 | | |
Mariola Fotin-Mleczek
|
| | | | vS | | | | | | 33,268 | | | | | | 33,268 | | | | | | | | | | | | 01.01.2013 | | | | | | 36 | | | |
之前的VSOP
|
| | | | 31.12.2025 | | |
Mariola Fotin-Mleczek
|
| | | | vS | | | | | | 33,268 | | | | | | 33,268 | | | | | | | | | | | | 01.01.2014 | | | | | | 36 | | | |
之前的VSOP
|
| | | | 31.12.2025 | | |
Mariola Fotin-Mleczek
|
| | | | vS | | | | | | 33,268 | | | | | | 33,268 | | | | | | | | | | | | 01.01.2015 | | | | | | 36 | | | |
之前的VSOP
|
| | | | 31.12.2025 | | |
Mariola Fotin-Mleczek
|
| | | | vS | | | | | | 309,671 | | | | | | 309,671 | | | | | | | | | | | | 01.01.2015 | | | | | | 12 | | | |
之前的VSOP
|
| | | | 31.12.2025 | | |
Ulrike Gnad-Vogt
|
| | | | vS | | | | | | 90,751 | | | | | | 90,751 | | | | | | | | | | | | 01.07.2011 | | | | | | 60 | | | |
之前的VSOP
|
| | | | 31.12.2025 | | |
Ulrike Gnad-Vogt
|
| | | | vS | | | | | | 33,268 | | | | | | 33,268 | | | | | | | | | | | | 01.01.2013 | | | | | | 36 | | | |
之前的VSOP
|
| | | | 31.12.2025 | | |
Ulrike Gnad-Vogt
|
| | | | vS | | | | | | 33,268 | | | | | | 33,268 | | | | | | | | | | | | 01.01.2014 | | | | | | 36 | | | |
之前的VSOP
|
| | | | 31.12.2025 | | |
Ulrike Gnad-Vogt
|
| | | | vS | | | | | | 33,268 | | | | | | 33,268 | | | | | | | | | | | | 01.01.2015 | | | | | | 36 | | | |
之前的VSOP
|
| | | | 31.12.2025 | | |
Ulrike Gnad-Vogt
|
| | | | vS | | | | | | 260,964 | | | | | | 260,964 | | | | | | | | | | | | 01.01.2015 | | | | | | 12 | | | |
之前的VSOP
|
| | | | 31.12.2025 | | |
弗朗茨-维尔纳·哈斯
|
| | | | vS | | | | | | 186,307 | | | | | | 186,307 | | | | | | | | | | | | 01.06.2012 | | | | | | 36 | | | |
之前的VSOP
|
| | | | 31.12.2025 | | |
弗朗茨-维尔纳·哈斯
|
| | | | vS | | | | | | 479,079 | | | | | | 479,079 | | | | | | | | | | | | 01.01.2013 | | | | | | 36 | | | |
之前的VSOP
|
| | | | 31.12.2025 | | |
弗朗茨-维尔纳·哈斯
|
| | | | vS | | | | | | 202,543 | | | | | | 202,543 | | | | | | | | | | | | 01.01.2015 | | | | | | 12 | | | |
之前的VSOP
|
| | | | 31.12.2025 | | |
皮埃尔·科穆拉
|
| | | | vS | | | | | | 665,388 | | | | | | 665,388 | | | | | | 01.10.2016 | | | | | | 18.04.2019 | | | | | | 36 | | | |
之前的VSOP
|
| | | | 31.12.2025 | | |
丹尼尔·梅尼切拉*
|
| | | | * | | | | | | 3,866,308 | | | | | | 3,866,308 | | | | | | 08.01.2017 | | | | | | 14.10.2019 | | | | | | 48 | | | | * | | | | | 08.01.2027 | | |
| | |
股票受益
在此之前拥有的 提供服务 |
| |
普通股受益
此 生效后拥有 提供服务 |
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不锻炼
承销商的 的 选项 |
| |
全面锻炼
承销商的 的 选项 |
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股东
|
| |
号码
|
| |
百分比
|
| |
号码
|
| |
百分比
|
| |
百分比
|
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5%股东: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
Dievini Hopp Biotech Holding GmbH&Co.Kg(1)
|
| | | | 79,775,217 | | | | | | 44.03% | | | | | | 79,775,217 | | | | | | 42.85% | | | | | | 42.68% | | |
OH Beteiligungen GmbH&Co.kg(4)
|
| | | | 79,775,217 | | | | | | 44.03% | | | | | | 79,775,217 | | | | | | 42.85% | | | | | | 42.68% | | |
DH-Capital GmbH&Co.kg(4)
|
| | | | 79,775,217 | | | | | | 44.03% | | | | | | 79,775,217 | | | | | | 42.85% | | | | | | 42.68% | | |
Kreditanstalt毛皮Wiederaufbau(2)
|
| | | | 29,871,441 | | | | | | 16.49% | | | | | | 29,871,441 | | | | | | 16.05% | | | | | | 15.98% | | |
葛兰素史克集团有限公司
|
| | | | 14,935,721 | | | | | | 8.24% | | | | | | 14,935,721 | | | | | | 8.02% | | | | | | 7.99% | | |
管理董事: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
弗洛里安·冯德·穆尔贝,博士,MBA
|
| | | | 1,257,147 | | | | | | *% | | | | | | 1,257,147 | | | | | | *% | | | | | | *% | | |
Mariola Fotin - Mleczek博士
|
| | | | 45,887 | | | | | | *% | | | | | | 45,887 | | | | | | *% | | | | | | *% | | |
Franz - Werner Haas,法律系,法律系
|
| | | | 87,527 | | | | | | *% | | | | | | 87,527 | | | | | | *% | | | | | | *% | | |
皮埃尔·科米拉,B.Sc.
|
| | | | 67,273 | | | | | | *% | | | | | | 67,273 | | | | | | *% | | | | | | *% | | |
监事长: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
拉尔夫·克莱门斯医学博士
|
| | | | — | | | | | | —% | | | | | | — | | | | | | —% | | | | | | —% | | |
Mathias Hothum博士(3)
|
| | | | 79,775,217 | | | | | | 44.03% | | | | | | 79,775,217 | | | | | | 42.85% | | | | | | 42.68% | | |
Jean Stephenne男爵,MBA硕士
|
| | | | — | | | | | | —% | | | | | | — | | | | | | —% | | | | | | —% | | |
| | |
股票受益
在此之前拥有的 提供服务 |
| |
普通股受益
此 生效后拥有 提供服务 |
| ||||||||||||||||||||||||
| | | | | | | | | | | | | | |
不锻炼
承销商的 的 选项 |
| |
全面锻炼
承销商的 的 选项 |
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股东
|
| |
号码
|
| |
百分比
|
| |
号码
|
| |
百分比
|
| |
百分比
|
| |||||||||||||||
汉斯·克里斯托夫·坦纳(Hans Cristoph Tanner)博士
|
| | | | 188,172 | | | | | | *% | | | | | | 188,172 | | | | | | *% | | | | | | *% | | |
Friedrich von Bohlen und Halbach,Ph.D.(3)
|
| | | | 80,017,152 | | | | | | 44.17% | | | | | | 80,017,152 | | | | | | 42.98% | | | | | | 42.81% | | |
医学博士蒂莫西·M·赖特
|
| | | | — | | | | | | —% | | | | | | — | | | | | | —% | | | | | | —% | | |
克雷格·A·图曼(Craig A.Tooman),MBA
|
| | | | — | | | | | | —% | | | | | | — | | | | | | —% | | | | | | —% | | |
全体常务董事和监事长合计:
|
| | | | 81,663,159 | | | | | | 45.08% | | | | | | 81,663,159 | | | | | | 43.87% | | | | | | 43.69% | | |
承销商
|
| |
号码
共 个共享 |
| |||
美国银行证券公司
|
| | | | 1,854,500 | | |
Jefferies LLC
|
| | | | 1,697,000 | | |
Evercore Group L.L.C.
|
| | | | 588,500 | | |
瑞银证券有限责任公司
|
| | | | 271,500 | | |
古根海姆证券有限责任公司
|
| | | | 271,500 | | |
Berenberg Capital Markets LLC
|
| | | | 158,500 | | |
Kempen&Co U.S.A.,Inc.
|
| | | | 158,500 | | |
合计
|
| | | | 5,000,000 | | |
| | |
每股
|
| |
不带选项
|
| |
带选项
|
| |||||||||
公开发行价
|
| | | $ | 90.00 | | | | | $ | 450,000,000 | | | | | $ | 517,500,000 | | |
承保折扣
|
| | | $ | 4.50 | | | | | $ | 22,500,000 | | | | | $ | 25,875,000 | | |
未扣除费用的收益给我们
|
| | | $ | 85.50 | | | | | $ | 427,500,000 | | | | | $ | 491,625,000 | | |
费用
|
| |
金额
|
| |||
美国证券交易委员会注册费
|
| | | $ | 64,999 | | |
FINRA申请费
|
| | | | 86,750 | | |
印刷费和雕刻费
|
| | | | 175,000 | | |
律师费和开支
|
| | | | 490,840 | | |
会计费和费用
|
| | | | 175,000 | | |
杂项成本
|
| | | | 55,888 | | |
合计
|
| | | $ | 1,048,477 | | |
| 未经审计的中期合并合并财务报表 - CureVac N.V. | | | | | | | |
|
截至2019年9月30日和2020年9月30日的9个月的中期精简合并经营报表和其他全面收益(亏损)
|
| | | | F-2 | | |
|
截至2019年12月31日和2020年9月30日的中期简明合并财务状况表
|
| | | | F-3 | | |
|
截至2019年9月30日和2020年9月30日的9个月的中期简明合并股东权益变动表
|
| | | | F-4 | | |
|
截至2019年9月30日和2020年9月30日的9个月中期简明合并现金流量表
|
| | | | F-5 | | |
|
截至2019年9月30日和2020年9月30日的9个月未经审计中期简明合并财务报表附注
|
| | | | F-6 | | |
| 合并财务报表 - CureVac AG | | | | | | | |
|
独立注册会计师事务所报告
|
| | | | F-17 | | |
|
截至2018年12月31日和2019年12月31日的合并经营报表和其他全面收益(亏损)
|
| | | | F-18 | | |
|
截至2018年12月31日和2019年12月31日的合并财务状况报表
|
| | | | F-19 | | |
|
截至2018年12月31日和2019年12月31日的年度股东权益变动合并报表
|
| | | | F-20 | | |
|
截至2018年12月31日和2019年12月31日的年度合并现金流量表
|
| | | | F-21 | | |
|
截至2018年12月31日和2019年12月31日的年度合并财务报表附注
|
| | | | F-22 | | |
| | | | | | | | |
截至9个月
09月30日 |
| |||||||||
| | |
备注
|
| |
2019
|
| |
2020
|
| |||||||||
(单位为千欧元,不包括每股金额)
|
| | | | | | | |
(未审核)
|
| |||||||||
收入
|
| | | | 3.1 | | | | | | 10,600 | | | | | | 42,830 | | |
销售成本
|
| | | | 3.2 | | | | | | (18,872) | | | | | | (7,049) | | |
销售和分销费用
|
| | | | 3.3 | | | | | | (485) | | | | | | (809) | | |
研发费用
|
| | | | 3.4 | | | | | | (30,665) | | | | | | (76,337) | | |
一般和行政费用
|
| | | | 3.5 | | | | | | (28,504) | | | | | | (33,147) | | |
其他营业收入
|
| | | | 3.6 | | | | | | 3,838 | | | | | | 11,695 | | |
其他运营费用
|
| | | | | | | | | | (339) | | | | | | (357) | | |
营业亏损
|
| | | | | | | | | | (64,427) | | | | | | (63,174) | | |
财务收入
|
| | | | | | | | | | 3,133 | | | | | | 5,103 | | |
财务费用
|
| | | | | | | | | | (2,924) | | | | | | (14,519) | | |
所得税前亏损
|
| | | | | | | | | | (64,218) | | | | | | (72,590) | | |
所得税优惠/(费用)
|
| | | | | | | | | | 335 | | | | | | 1,615 | | |
该期间的净亏损
|
| | | | | | | | | | (63,883) | | | | | | (70,975) | | |
其他综合收益: | | | | | | | | | | | | | | | | | | | |
随后可能重新分类为损益的项目 | | | | | | | | | | | | | | | | | | | |
外币调整
|
| | | | | | | | | | (20) | | | | | | 76 | | |
本期综合亏损总额
|
| | | | | | | | | | (63,903) | | | | | | (70,899) | | |
每股净亏损(基本和稀释后)*
|
| | | | | | | | | | (0.66) | | | | | | (0.61) | | |
| | |
备注
|
| |
12月31日
2019 |
| |
09月30日
2020 |
| |||||||||
(千欧元)
|
| | | | | | | | | | | | | |
(未审核)
|
| |||
资产 | | | | | | | | | | | | | | | | | | | |
非流动资产 | | | | | | | | | | | | | | | | | | | |
无形资产
|
| | | | 6.1 | | | | | | 5,698 | | | | | | 10,138 | | |
物业、厂房和设备
|
| | | | 6.2 | | | | | | 48,075 | | | | | | 59,364 | | |
使用权资产
|
| | | | 6.3 | | | | | | 13,611 | | | | | | 34,693 | | |
其他资产
|
| | | | 6.4 | | | | | | 6,061 | | | | | | 2,147 | | |
递延税金资产
|
| | | | | | | | | | — | | | | | | 65 | | |
非流动资产合计
|
| | | | | | | | | | 73,445 | | | | | | 106,407 | | |
流动资产 | | | | | | | | | | | | | | | | | | | |
库存
|
| | | | 8 | | | | | | 6,197 | | | | | | 1,426 | | |
贸易应收账款
|
| | | | | | | | | | 15,690 | | | | | | — | | |
合同资产
|
| | | | | | | | | | 1,463 | | | | | | 535 | | |
其他金融资产
|
| | | | 9 | | | | | | 1,458 | | | | | | 1,129 | | |
预付费用和其他资产
|
| | | | 7 | | | | | | 1,683 | | | | | | 20,011 | | |
现金和现金等价物
|
| | | | | | | | | | 30,684 | | | | | | 892,399 | | |
流动资产总额
|
| | | | | | | | | | 57,175 | | | | | | 915,500 | | |
总资产
|
| | | | | | | | | | 130,620 | | | | | | 1,021,907 | | |
股权和负债 | | | | | | | | | | | | | | | | | | | |
股权
|
| | | | 4 | | | | | | | | | | | | | | |
已发行资本*
|
| | | | | | | | | | 11,603 | | | | | | 21,560 | | |
资本公积*
|
| | | | | | | | | | 461,520 | | | | | | 1,326,766 | | |
累计亏损
|
| | | | | | | | | | (515,947) | | | | | | (586,922) | | |
其他综合收益
|
| | | | | | | | | | 22 | | | | | | (54) | | |
总股本
|
| | | | | | | | | | (42,802) | | | | | | 761,350 | | |
非流动负债 | | | | | | | | | | | | | | | | | | | |
可转换贷款
|
| | | | 11 | | | | | | 65,018 | | | | | | — | | |
租赁负债
|
| | | | | | | | | | 12,126 | | | | | | 27,724 | | |
合同责任
|
| | | | 3.1 | | | | | | 66,040 | | | | | | 121,778 | | |
递延纳税义务
|
| | | | | | | | | | 1,623 | | | | | | — | | |
其他负债
|
| | | | | | | | | | 530 | | | | | | 530 | | |
非流动负债合计
|
| | | | | | | | | | 145,336 | | | | | | 150,032 | | |
流动负债 | | | | | | | | | | | | | | | | | | | |
租赁负债
|
| | | | | | | | | | 2,004 | | | | | | 2,921 | | |
贸易和其他应付款
|
| | | | 10 | | | | | | 6,475 | | | | | | 50,225 | | |
其他负债
|
| | | | | | | | | | 12,015 | | | | | | 27,052 | | |
应付所得税
|
| | | | | | | | | | 111 | | | | | | 130 | | |
合同责任
|
| | | | 3.1 | | | | | | 7,481 | | | | | | 30,197 | | |
流动负债总额
|
| | | | | | | | | | 28,086 | | | | | | 110,525 | | |
总负债
|
| | | | | | | | | | 173,422 | | | | | | 260,557 | | |
总权益和负债
|
| | | | | | | | | | 130,620 | | | | | | 1,021,907 | | |
(千欧元)
|
| |
已发布
大写* |
| |
大写
预订* |
| |
累计
赤字 |
| |
币种
翻译 预订 |
| |
合计
股权 |
| |||||||||||||||
截至2020年1月1日的余额
|
| | | | 11,603 | | | | | | 461,520 | | | | | | (515,947) | | | | | | 22 | | | | | | (42,802) | | |
净亏损
|
| | | | — | | | | | | — | | | | | | (70,975) | | | | | | — | | | | | | (70,975) | | |
其他综合收益(亏损)
|
| | | | — | | | | | | — | | | | | | — | | | | | | (76) | | | | | | (76) | | |
综合收益(亏损)合计
|
| | |
|
—
|
| | | |
|
—
|
| | | | | (70,975) | | | | | | (76) | | | | | | (71,051) | | |
股份支付费用
|
| | | | — | | | | | | 7,399 | | | | | | — | | | | | | — | | | | | | 7,399 | | |
可转换贷款的权益部分(税后净额)
|
| | | | — | | | | | | 87 | | | | | | — | | | | | | — | | | | | | 87 | | |
期权的行使
|
| | | | 288 | | | | | | (288) | | | | | | — | | | | | | — | | | | | | — | | |
发行股本(扣除交易成本)
|
| | | | 9,669 | | | | | | 858,048 | | | | | | — | | | | | | — | | | | | | 867,717 | | |
截至2020年9月30日的余额(未经审计)
|
| | | | 21,560 | | | | | | 1,326,766 | | | | | | (586,922) | | | | | | (54) | | | | | | 761,350 | | |
(千欧元)
|
| |
已发布
大写* |
| |
大写
预订* |
| |
累计
赤字 |
| |
币种
翻译 预订 |
| |
合计
股权 |
| |||||||||||||||
截至2019年1月1日的余额
|
| | | | 11,603 | | | | | | 436,564 | | | | | | (416,074) | | | | | | (10) | | | | | | 32,083 | | |
净亏损
|
| | | | — | | | | | | — | | | | | | (64,671) | | | | | | — | | | | | | (64,671) | | |
其他综合收益
|
| | | | — | | | | | | — | | | | | | — | | | | | | 21 | | | | | | 21 | | |
综合收益(亏损)合计
|
| | |
|
—
|
| | | |
|
—
|
| | | | | (64,671) | | | | | | 21 | | | | | | (64,650) | | |
股份支付费用
|
| | | | — | | | | | | 6,073 | | | | | | — | | | | | | — | | | | | | 6,073 | | |
可转换贷款的权益部分(税后净额)
|
| | | | — | | | | | | 5,744 | | | | | | — | | | | | | — | | | | | | 5,744 | | |
截至2019年9月30日的余额(未经审计)
|
| | | | 11,603 | | | | | | 448,381 | | | | | | (480,745) | | | | | | 11 | | | | | | (20,750) | | |
| | |
截至9个月
09月30日 |
| |||||||||
| | |
2019
|
| |
2020
|
| ||||||
(千欧元)
|
| |
(未审核)
|
| |||||||||
经营活动 | | | | | | | | | | | | | |
所得税前亏损
|
| | |
|
(64,218)
|
| | | |
|
(72,590)
|
| |
调整税前亏损至净现金流 | | | | | | | | | | | | | |
财务收入
|
| | | | (3,133) | | | | | | (5,103) | | |
财务费用
|
| | | | 2,924 | | | | | | 14,519 | | |
折旧摊销
|
| | | | 4,924 | | | | | | 7,244 | | |
固定资产处置损失
|
| | | | 46 | | | | | | 357 | | |
股份支付费用
|
| | | | 6,074 | | | | | | 7,399 | | |
营运资金变动 | | | | | | | | | | | | | |
贸易应收账款和合同资产减少/(增加)
|
| | | | 1,707 | | | | | | 16,662 | | |
库存减少/(增加)
|
| | | | (4,442) | | | | | | 4,775 | | |
预付费用和其他资产减少/(增加)
|
| | | | (765) | | | | | | (19,336) | | |
政府机构和类似机构的赠款收据
|
| | | | 2,178 | | | | | | 17,630 | | |
(减少)/贸易及其他应付款和合同负债增加
|
| | | | (11,912) | | | | | | 116,457 | | |
递延税金减少/(增加)
|
| | | | (312) | | | | | | (65) | | |
(减少)/增加其他流动财务和其他负债
|
| | | | (417) | | | | | | — | | |
缴纳所得税
|
| | | | — | | | | | | (98) | | |
已支付利息
|
| | | | (633) | | | | | | (6,869) | | |
经营活动提供(用于)的净现金流
|
| | | | (67,979) | | | | | | 80,982 | | |
投资活动 | | | | | | | | | | | | | |
购置房产、厂房和设备
|
| | | | (6,629) | | | | | | (15,149) | | |
购买无形资产
|
| | | | (681) | | | | | | (5,883) | | |
资产相关赠款收益
|
| | | | 1,501 | | | | | | 3,237 | | |
出售其他金融资产的收益
|
| | | | 38,856 | | | | | | 329 | | |
投资活动提供(用于)的净现金流
|
| | | | 33,047 | | | | | | (17,466) | | |
融资活动 | | | | | | | | | | | | | |
租赁债务付款
|
| | | | (1,331) | | | | | | (3,478) | | |
股票发行收益(扣除交易成本)
|
| | | | — | | | | | | 867,717 | | |
可转换贷款收益
|
| | | | 50,000 | | | | | | 24,860 | | |
偿还可转换贷款
|
| | | | — | | | | | | (94,749) | | |
融资活动提供的净现金流
|
| | | | 48,669 | | | | | | 794,350 | | |
现金和现金等价物的货币换算收益(亏损)
|
| | | | (139) | | | | | | 3,849 | | |
现金和现金等价物增加
|
| | | | 13,737 | | | | | | 857,867 | | |
期初现金和现金等价物
|
| | | | 21,750 | | | | | | 30,684 | | |
现金和现金等价物,期末
|
| | | | 35,348 | | | | | | 892,399 | | |
| | |
截至9个月
09月30日 |
| |||||||||
| | |
2019
|
| |
2020
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
美国 | | | | | | | | | | | | | |
礼来公司
|
| | | | 8,694 | | | | | | 34,854 | | |
德国 | | | | | | | | | | | | | |
勃林格-英格尔海姆
|
| | | | 1,569 | | | | | | 1,418 | | |
瑞士 | | | | | | | | | | | | | |
CRISPR
|
| | | | 337 | | | | | | 618 | | |
荷兰 | | | | | | | | | | | | | |
Genmab
|
| | | | — | | | | | | 1,893 | | |
比利时 | | | | | | | | | | | | | |
葛兰素史克
|
| | | | — | | | | | | 4,047 | | |
合计 | | | | | 10,600 | | | | | | 42,830 | | |
| | |
预付款
2020年9月30日 |
| |
预付
付款 包含在 中 合同 负债 |
| |
预付
付款 包含在 中 合同 负债 |
| |
确认的收入
预付款 截至 的9个月 09月30日 |
| |||||||||||||||
客户
|
| |
09月30日
2019 |
| |
09月30日
2020 |
| |
2019
|
| |
2020
|
| |||||||||||||||
| | |
(千)
|
| |
(欧元k)
|
| |
(欧元k)
|
| |
(欧元k)
|
| |||||||||||||||
礼来公司
|
| |
5万美元(42,200欧元)*
|
| | | | 35,733 | | | | | | — | | | | | | 2,637 | | | | | | 34,854 | | |
CRISPR
|
| | 3000美元(2524欧元)* | | | | | 1,936 | | | | | | 1,627 | | | | | | 232 | | | | | | 232 | | |
勃林格-英格尔海姆
|
| | 3万欧元 | | | | | 16,336 | | | | | | 14,469 | | | | | | 1,485 | | | | | | 1,400 | | |
Genmab
|
| |
1万美元(8937欧元)*
|
| | | | — | | | | | | 7,597 | | | | | | — | | | | | | 1,341 | | |
葛兰素史克
|
| | 12万欧元 | | | | | — | | | | | | 116,255 | | | | | | — | | | | | | 3,718 | | |
合计 | | | | | | | | 54,006 | | | | | | 139,948 | | | | | | 4,354 | | | | | | 41,545 | | |
合同余额:
|
| |
12月31日
2019 |
| |
09月30日
2020 |
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
贸易应收账款
|
| | | | 15,690 | | | | | | — | | |
合同资产
|
| | | | 1,463 | | | | | | 535 | | |
合同责任
|
| | | | 73,521 | | | | | | 151,975 | | |
| | |
截至9个月
09月30日 |
| |||||||||
| | |
2019
|
| |
2020
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
人员
|
| | | | (7,249) | | | | | | (2,171) | | |
材料
|
| | | | (4,022) | | | | | | (1,380) | | |
第三方服务
|
| | | | (5,339) | | | | | | (2,432) | | |
维护和租赁
|
| | | | (770) | | | | | | (752) | | |
摊销折旧
|
| | | | (1,259) | | | | | | (250) | | |
其他
|
| | | | (233) | | | | | | (64) | | |
合计 | | | | | (18,872) | | | | | | (7,049) | | |
| | |
截至9个月
09月30日 |
| |||||||||
| | |
2019
|
| |
2020
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
人员
|
| | | | (257) | | | | | | (755) | | |
摊销折旧
|
| | | | (61) | | | | | | (77) | | |
其他
|
| | | | (167) | | | | | | 23 | | |
合计 | | | | | (485) | | | | | | (809) | | |
| | |
截至9个月
09月30日 |
| |||||||||
| | |
2019
|
| |
2020
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
材料
|
| | | | (2,605) | | | | | | (21,595) | | |
人员
|
| | | | (9,321) | | | | | | (16,213) | | |
摊销折旧
|
| | | | (895) | | | | | | (2,589) | | |
注册合法权利的专利和费用
|
| | | | (3,143) | | | | | | (3,525) | | |
第三方服务
|
| | | | (14,426) | | | | | | (27,973) | | |
维护和租赁
|
| | | | (20) | | | | | | (560) | | |
其他
|
| | | | (255) | | | | | | (3,882) | | |
合计 | | | | | (30,665) | | | | | | (76,337) | | |
| | |
截至9个月
09月30日 |
| |||||||||
| | |
2019
|
| |
2020
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
人员
|
| | | | (16,747) | | | | | | (15,847) | | |
维护和租赁
|
| | | | (2,138) | | | | | | (1,571) | | |
第三方服务
|
| | | | (4,203) | | | | | | (5,097) | | |
法律和其他专业服务
|
| | | | (825) | | | | | | (2,276) | | |
摊销折旧
|
| | | | (2,709) | | | | | | (4,382) | | |
其他
|
| | | | (1,882) | | | | | | (3,974) | | |
合计 | | | | | (28,504) | | | | | | (33,147) | | |
| | |
截至9个月
09月30日 |
| |||||||||
| | |
2019
|
| |
2020
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
政府机构和类似机构提供的补助金和其他费用报销
|
| | | | 3,781 | | | | | | 11,313 | | |
其他
|
| | | | 57 | | | | | | 382 | | |
合计 | | | | | 3,838 | | | | | | 11,695 | | |
| | |
截至9个月
09月30日 |
| ||||||
| | |
2019
|
| |
2020
|
| |||
| | |
欧元k
|
| |
欧元k
|
| |||
研发费用
|
| | | | — | | | |
2,985
|
|
销售和营销费用
|
| | | | — | | | |
467
|
|
一般和行政费用
|
| | | | 6,074 | | | |
3,947
|
|
合计 | | | | | 6,074 | | | |
7,399
|
|
| | |
截至9个月
09月30日 |
| |||||||||
计划
|
| |
2019
|
| |
2020
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
前首席执行官格兰特
|
| | | | — | | | | | | 2,551 | | |
新的VSOP
|
| | | | — | | | | | | 1,327 | | |
之前的VSOP
|
| | | | 6,074 | | | | | | 3,521 | | |
合计 | | | | | 6,074 | | | | | | 7,399 | | |
| | | | | | | | |
截至2013年12月31日的年度
|
| |||||||||
(单位为千欧元,每股数据除外)
|
| |
备注
|
| |
2018
|
| |
2019
|
| |||||||||
收入
|
| | | | 3.1 | | | | | | 12,871 | | | | | | 17,416 | | |
销售成本
|
| | | | 3.2 | | | | | | (17,744) | | | | | | (27,983) | | |
销售和分销费用
|
| | | | 3.3 | | | | | | (1,085) | | | | | | (1,755) | | |
研发费用
|
| | | | 3.4 | | | | | | (41,722) | | | | | | (43,242) | | |
一般和行政费用
|
| | | | 3.5 | | | | | | (25,289) | | | | | | (48,969) | | |
其他营业收入
|
| | | | 3.6 | | | | | | 808 | | | | | | 5,587 | | |
其他运营费用
|
| | | | 3.7 | | | | | | (663) | | | | | | (552) | | |
营业亏损
|
| | | | | | | | | | (72,824) | | | | | | (99,498) | | |
财务收入
|
| | | | | | | | | | 1,968 | | | | | | 833 | | |
财务费用
|
| | | | | | | | | | (275) | | | | | | (1,460) | | |
所得税前亏损
|
| | | | | | | | | | (71,131) | | | | | | (100,125) | | |
所得税优惠/(费用)
|
| | | | 14 | | | | | | (110) | | | | | | 252 | | |
本年度净亏损
|
| | | | | | | | | | (71,241) | | | | | | (99,873) | | |
其他综合收益 | | | | | | | | | | | | | | | | | | | |
随后可能重新分类为损益的项目 | | | | | | | | | | | | | | | | | | | |
外币调整
|
| | | | | | | | | | 66 | | | | | | 32 | | |
本年度综合亏损总额
|
| | | | | | | | | | (71,175) | | | | | | (99,841) | | |
每股净亏损(基本和稀释后)*
|
| | | | | | | | | | (0.74) | | | | | | (1.03) | | |
| | | | | | | | |
12月31日
|
| |||||||||
(千欧元)
|
| |
备注
|
| |
2018
|
| |
2019
|
| |||||||||
资产 | | | | | | | | | | | | | | | | | | | |
非流动资产 | | | | | | | | | | | | | | | | | | | |
无形资产
|
| | | | 4 | | | | | | 6,213 | | | | | | 5,698 | | |
物业、厂房和设备
|
| | | | 4 | | | | | | 40,472 | | | | | | 48,075 | | |
其他资产
|
| | | | 4 | | | | | | 5,771 | | | | | | 6,061 | | |
使用权资产
|
| | | | 2 | | | | | | — | | | | | | 13,611 | | |
递延税金资产
|
| | | | 14 | | | | | | 133 | | | | | | — | | |
非流动资产合计
|
| | | | | | | | | | 52,589 | | | | | | 73,445 | | |
流动资产 | | | | | | | | | | | | | | | | | | | |
库存
|
| | | | 5 | | | | | | 2,951 | | | | | | 6,197 | | |
贸易应收账款
|
| | | | 3 | | | | | | 5,476 | | | | | | 15,690 | | |
合同资产
|
| | | | 3 | | | | | | 1,382 | | | | | | 1,463 | | |
其他金融资产
|
| | | | 6 | | | | | | 39,253 | | | | | | 1,458 | | |
预付费用和其他资产
|
| | | | 7 | | | | | | 2,628 | | | | | | 1,683 | | |
现金和现金等价物
|
| | | | | | | | | | 21,380 | | | | | | 30,684 | | |
流动资产总额
|
| | | | | | | | | | 73,070 | | | | | | 57,175 | | |
总资产
|
| | | | | | | | | | 125,659 | | | | | | 130,620 | | |
股权和负债 | | | | | | | | | | | | | | | | | | | |
股权 | | | | | | | | | | | | | | | | | | | |
已发行资本*
|
| | | | | | | | | | 11,610 | | | | | | 11,610 | | |
资本公积*
|
| | | | | | | | | | 436,557 | | | | | | 461,513 | | |
累计亏损
|
| | | | | | | | | | (416,074) | | | | | | (515,947) | | |
其他综合收益
|
| | | | | | | | | | (10) | | | | | | 22 | | |
总股本
|
| | | | 8 | | | | | | 32,083 | | | | | | (42,802) | | |
非流动负债 | | | | | | | | | | | | | | | | | | | |
可转换贷款
|
| | | | 12 | | | | | | — | | | | | | 65,018 | | |
租赁负债
|
| | | | 2 | | | | | | — | | | | | | 12,126 | | |
合同责任
|
| | | | 3 | | | | | | 64,583 | | | | | | 66,040 | | |
递延纳税义务
|
| | | | 13 | | | | | | — | | | | | | 1,623 | | |
其他负债
|
| | | | | | | | | | 863 | | | | | | 529 | | |
非流动负债合计
|
| | | | | | | | | | 65,446 | | | | | | 145,336 | | |
流动负债 | | | | | | | | | | | | | | | | | | | |
其他金融负债
|
| | | | | | | | | | 77 | | | | | | — | | |
租赁负债
|
| | | | 2 | | | | | | — | | | | | | 2,004 | | |
贸易和其他应付款
|
| | | | 11 | | | | | | 10,913 | | | | | | 6,475 | | |
其他负债
|
| | | | 12 | | | | | | 11,146 | | | | | | 12,015 | | |
应付所得税
|
| | | | 13 | | | | | | 217 | | | | | | 111 | | |
合同责任
|
| | | | 3 | | | | | | 5,777 | | | | | | 7,481 | | |
流动负债总额
|
| | | | | | | | | | 28,130 | | | | | | 28,086 | | |
总负债
|
| | | | | | | | | | 93,576 | | | | | | 173,422 | | |
总权益和负债
|
| | | | | | | | | | 125,659 | | | | | | 130,620 | | |
(千欧元)
|
| |
已发布
大写* |
| |
大写
预订* |
| |
累计
赤字 |
| |
币种
翻译 预订 |
| |
总股本
|
| |||||||||||||||
截至2018年1月1日的余额
|
| | | | 11,610 | | | | | | 436,555 | | | | | | (345,320) | | | | | | (76) | | | | | | 102,769 | | |
首次采用IFRS 9的影响
|
| | | | — | | | | | | — | | | | | | (183) | | | | | | — | | | | | | (183) | | |
首次采用IFRS 15的影响
|
| | | | — | | | | | | — | | | | | | 670 | | | | | | — | | | | | | 670 | | |
截至2018年1月1日调整后余额
|
| | | | 11,610 | | | | | | 436,555 | | | | | | (344,833) | | | | | | (76) | | | | | | 103,256 | | |
净亏损
|
| | | | — | | | | | | — | | | | | | (71,241) | | | | | | — | | | | | | (71,241) | | |
其他综合收益(亏损)
|
| | | | — | | | | | | — | | | | | | — | | | | | | 66 | | | | | | 66 | | |
综合收益(亏损)合计
|
| | | | — | | | | | | — | | | | | | (71,241) | | | | | | 66 | | | | | | (71,175) | | |
股份支付计划的费用
|
| | | | — | | | | | | 2 | | | | | | — | | | | | | — | | | | | | 2 | | |
截至2018年12月31日的余额
|
| | | | 11,610 | | | | | | 436,557 | | | | | | (416,074) | | | | | | (10) | | | | | | 32,083 | | |
净亏损
|
| | | | — | | | | | | — | | | | | | (99,873) | | | | | | — | | | | | | (99,873) | | |
其他综合收益(亏损)
|
| | | | — | | | | | | — | | | | | | — | | | | | | 32 | | | | | | 32 | | |
综合收益(亏损)合计
|
| | | | — | | | | | | — | | | | | | (99,873) | | | | | | 32 | | | | | | (99,841) | | |
可转换贷款的权益部分
|
| | | | — | | | | | | 7,604 | | | | | | — | | | | | | — | | | | | | 7,604 | | |
可转换贷款递延税款
|
| | | | — | | | | | | (2,212) | | | | | | — | | | | | | — | | | | | | (2,212) | | |
股份支付计划的费用
|
| | | | — | | | | | | 19,564 | | | | | | — | | | | | | — | | | | | | 19,564 | | |
截至2019年12月31日的余额
|
| | | | 11,610 | | | | | | 461,513 | | | | | | (515,947) | | | | | | 22 | | | | | | (42,802) | | |
| | |
截至2013年12月31日的年度
|
| |||||||||
(千欧元)
|
| |
2018
|
| |
2019
|
| ||||||
经营活动 | | | | | | | | | | | | | |
所得税前亏损
|
| | | | (71,131) | | | | | | (100,125) | | |
调整税前亏损至净现金流 | | | | | | | | | | | | | |
财务收入
|
| | | | (1,968) | | | | | | (833) | | |
财务费用
|
| | | | 275 | | | | | | 1,460 | | |
折旧摊销
|
| | | | 3,781 | | | | | | 7,164 | | |
固定资产处置损失
|
| | | | 52 | | | | | | 241 | | |
股份支付费用
|
| | | | (4,248) | | | | | | 19,564 | | |
营运资金变动 | | | | | | | | | | | | | |
贸易应收账款和合同资产减少/(增加)
|
| | | | (5,595) | | | | | | (10,117) | | |
库存减少/(增加)
|
| | | | 878 | | | | | | (3,246) | | |
其他资产减少/(增加)
|
| | | | (6,106) | | | | | | 630 | | |
政府机构和类似机构的赠款收据
|
| | | | 214 | | | | | | 9,304 | | |
(减少)/贸易及其他应付款和合同负债增加
|
| | | | 9,402 | | | | | | (9,584) | | |
(减少)/增加其他流动财务和其他负债
|
| | | | 336 | | | | | | (334) | | |
缴纳所得税
|
| | | | (26) | | | | | | (345) | | |
收到利息
|
| | | | 15 | | | | | | 81 | | |
已支付利息
|
| | | | 11 | | | | | | (824) | | |
净现金流量(用于)经营活动
|
| | | | (74,110) | | | | | | (86,963) | | |
投资活动 | | | | | | | | | | | | | |
购置房产、厂房和设备
|
| | | | (9,406) | | | | | | (11,172) | | |
购买无形资产
|
| | | | (5,317) | | | | | | (1,052) | | |
资产相关赠款收益
|
| | | | — | | | | | | 2,325 | | |
其他金融资产收益
|
| | | | 10,459 | | | | | | 38,080 | | |
投资活动产生(用于)的净现金流
|
| | | | (4,264) | | | | | | 28,181 | | |
融资活动 | | | | | | | | | | | | | |
租赁债务付款
|
| | | | (112) | | | | | | (1,910) | | |
可转换贷款收益
|
| | | | — | | | | | | 69,889 | | |
融资活动产生(用于)的净现金流
|
| | | | (112) | | | | | | 67,979 | | |
现金及现金等价物净增(减)
|
| | | | (78,486) | | | | | | 9,197 | | |
货币换算收益对现金和现金等价物的影响
|
| | | | 213 | | | | | | 107 | | |
期初现金和现金等价物
|
| | | | 99,653 | | | | | | 21,380 | | |
现金和现金等价物,期末
|
| | | | 21,380 | | | | | | 30,684 | | |
|
软件和许可证
|
| |
3到8年
|
|
|
建筑物:
|
| |
1至10年
|
|
|
技术装备和机器:
|
| |
3到14年
|
|
|
其他设备、家具和固定装置:
|
| |
3到14年
|
|
| | |
欧元k
|
| |||
截至2018年12月31日的现有承诺 | | | | | | | |
经营租赁承诺额
|
| | | | 48,008 | | |
融资租赁负债的最低租赁付款(名义金额)
|
| | | | 78 | | |
短期租赁的解除选项
|
| | | | (110) | | |
开始日期在2019年1月1日之后的租约,金额为上述截至2018年12月31日的现有承诺额
|
| | | | (28,557) | | |
其他
|
| | | | 123 | | |
截至2019年1月1日的总租赁负债
|
| | | | 19,542 | | |
打折效果
|
| | | | (3,655) | | |
截至2019年1月1日的租赁负债
|
| | | | 15,887 | | |
截至2018年12月31日融资租赁负债现值
|
| | | | (77) | | |
截至2019年1月1日首次应用IFRS第16号时的租赁负债
|
| | | | 15,810 | | |
截至2019年1月1日的加权平均增量借款利率
|
| | | | 5.64% | | |
|
土地和建筑:
|
| |
1至15年
|
|
|
车辆:
|
| |
3至4年
|
|
|
其他设备:
|
| |
2至5年
|
|
| | |
使用权资产
|
| |||||||||||||||||||||
| | |
土地和
建筑物 |
| |
车辆
|
| |
其他
设备 |
| |
合计
|
| ||||||||||||
| | |
欧元
|
| |
欧元
|
| |
欧元
|
| |
欧元
|
| ||||||||||||
截至2019年1月1日
|
| | | | 15,536 | | | | | | 132 | | | | | | 239 | | | | | | 15,907 | | |
添加
|
| | | | 82 | | | | | | 59 | | | | | | 13 | | | | | | 154 | | |
折旧费
|
| | | | (2,322) | | | | | | (65) | | | | | | (142) | | | | | | (2,529) | | |
外币折算
|
| | | | 79 | | | | | | — | | | | | | — | | | | | | 79 | | |
截至2019年12月31日
|
| | | | 13,375 | | | | | | 126 | | | | | | 110 | | | | | | 13,611 | | |
| | |
欧元k
|
| |||
截至2019年1月1日
|
| | |
|
15,887
|
| |
添加
|
| | | | 153 | | |
利息增值
|
| | | | 824 | | |
付款
|
| | | | (2,812) | | |
外币折算
|
| | | | 78 | | |
截至2019年12月31日
|
| | | | 14,130 | | |
当前
|
| | | | 2,004 | | |
非当前
|
| | | | 12,126 | | |
| | |
欧元k
|
| |||
使用权资产折旧费用
|
| | | | (2,529) | | |
租赁负债利息支出
|
| | | | (824) | | |
与短期租赁相关的费用(包括在销售成本中)
|
| | | | (167) | | |
低价资产租赁相关费用(计入行政费用)
|
| | | | (94) | | |
损益确认总额
|
| | | | (3,614) | | |
| | |
12月31日
2018 |
| |
12月31日
2019 |
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
美国 | | | | | | | | | | | | | |
礼来公司
|
| | | | 8,927 | | | | | | 14,319 | | |
德国 | | | | | | | | | | | | | |
勃林格-英格尔海姆
|
| | | | 3,337 | | | | | | 2,474 | | |
其他
|
| | | | 5 | | | | | | 104 | | |
瑞士 | | | | | | | | | | | | | |
CRISPR
|
| | | | 602 | | | | | | 519 | | |
合计
|
| | | | 12,871 | | | | | | 17,416 | | |
客户
|
| |
预付款
在 收到或应收 2019年12月31日 (千) |
| |
预付款
包含在 中 合同责任为 2019年12月31日 (欧元k) |
| |
确认的收入
预付款 (欧元k) |
| ||||||||||||
|
2018
|
| |
2019
|
| |||||||||||||||||
礼来公司
|
| |
5万美元(42,200欧元)
|
| | | | 34,854 | | | | | | 3,516 | | | | | | 3,516 | | |
CRISPR
|
| | 3000美元(2524欧元) | | | | | 1,859 | | | | | | 310 | | | | | | 310 | | |
勃林格-英格尔海姆
|
| | 3万欧元 | | | | | 15,870 | | | | | | 2,035 | | | | | | 1,951 | | |
Genmab
|
| | 1万美元(8937欧元) | | | | | 8,937 | | | | | | — | | | | | | — | | |
合计 | | | | | 61,520 | | | | | | 5,861 | | | | | | 5,777 | | |
| | |
1月1日
2018 |
| |
12月31日
2018 |
| |
12月31日
2019 |
| |||||||||
| | |
欧元k
|
| |
欧元k
|
| |
欧元k
|
| |||||||||
贸易应收账款
|
| | | | 463 | | | | | | 5,476 | | | | | | 15,690 | | |
合同资产
|
| | | | — | | | | | | 1,382 | | | | | | 1,463 | | |
合同责任
|
| | | | 69,220 | | | | | | 70,360 | | | | | | 73,521 | | |
| | |
年终
|
| |||||||||
| | |
2018
欧元k |
| |
2019
欧元k |
| ||||||
一年内
|
| | | | 5,777 | | | | | | 7,481 | | |
一年多
|
| | | | 64,583 | | | | | | 66,040 | | |
合计 | | | | | 70,360 | | | | | | 73,521 | | |
| | |
2018
|
| |
2019
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
人员
|
| | | | (7,703) | | | | | | (9,855) | | |
材料
|
| | | | (4,941) | | | | | | (7,542) | | |
第三方服务
|
| | | | (2,340) | | | | | | (7,268) | | |
维护和租赁
|
| | | | (1,758) | | | | | | (1,060) | | |
摊销折旧
|
| | | | (893) | | | | | | (2,038) | | |
其他
|
| | | | (109) | | | | | | (220) | | |
合计
|
| | | | (17,744) | | | | | | (27,983) | | |
| | |
2018
|
| |
2019
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
人员
|
| | | | (581) | | | | | | (1,263) | | |
维护和租赁成本
|
| | | | (300) | | | | | | (167) | | |
摊销折旧
|
| | | | (95) | | | | | | (81) | | |
其他
|
| | | | (109) | | | | | | (243) | | |
合计 | | | | | (1,085) | | | | | | (1,755) | | |
| | |
2018
|
| |
2019
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
材料
|
| | | | (5,867) | | | | | | (4,015) | | |
人员
|
| | | | (7,565) | | | | | | (14,385) | | |
摊销折旧
|
| | | | (1,143) | | | | | | (474) | | |
注册合法权利的专利和费用
|
| | | | (4,847) | | | | | | (4,551) | | |
第三方服务
|
| | | | (19,921) | | | | | | (18,626) | | |
维护和租赁
|
| | | | (1,156) | | | | | | (670) | | |
其他
|
| | | | (1,223) | | | | | | (521) | | |
合计 | | | | | (41,722) | | | | | | (43,242) | | |
| | |
2018
|
| |
2019
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
人员
|
| | | | (10,084) | | | | | | (31,645) | | |
维护和租赁成本
|
| | | | (3,239) | | | | | | (4,604) | | |
第三方服务
|
| | | | (4,006) | | | | | | (5,970) | | |
法律和其他专业服务
|
| | | | (4,078) | | | | | | (2,110) | | |
摊销折旧
|
| | | | (1,635) | | | | | | (2,182) | | |
其他
|
| | | | (2,247) | | | | | | (2,458) | | |
合计 | | | | | (25,289) | | | | | | (48,969) | | |
| | |
2018
|
| |
2019
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
政府机构和类似机构提供的补助金和其他费用报销
|
| | | | 808 | | | | | | 5,385 | | |
其他
|
| | | | — | | | | | | 202 | | |
合计
|
| | | | 808 | | | | | | 5,587 | | |
| | |
2018
|
| |
2019
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
监事会换届
|
| | | | (343) | | | | | | (521) | | |
其他
|
| | | | (320) | | | | | | (30) | | |
合计
|
| | | | (663) | | | | | | (552) | | |
(千欧元)
|
| |
软件和
许可证 |
| |
前进
付款 |
| |
合计
|
| |||||||||
采购成本 | | | | | | | | | | | | | | | | | | | |
截至2018年1月1日
|
| | | | 3,402 | | | | | | 235 | | | | | | 3,638 | | |
添加
|
| | | | 5,314 | | | | | | 2 | | | | | | 5,317 | | |
截至2018年12月31日
|
| | | | 8,717 | | | | | | 238 | | | | | | 8,954 | | |
累计摊销和减值费用 | | | | | | | | | | | | | | | | | | | |
截至2018年1月1日
|
| | | | 1,545 | | | | | | — | | | | | | 1,545 | | |
摊销
|
| | | | 1,197 | | | | | | — | | | | | | 1,197 | | |
截至2018年12月31日
|
| | | | 2,742 | | | | | | — | | | | | | 2,742 | | |
|
(千欧元)
|
| |
软件和
许可证 |
| |
前进
付款 |
| |
合计
|
| |||||||||
采购成本 | | | | | | | | | | | | | | | | | | | |
截至2019年1月1日
|
| | | | 8,717 | | | | | | 238 | | | | | | 8,954 | | |
添加
|
| | | | 738 | | | | | | 44 | | | | | | 782 | | |
处置
|
| | | | (6) | | | | | | — | | | | | | (6) | | |
截至2019年12月31日
|
| | | | 9,449 | | | | | | 282 | | | | | | 9,731 | | |
累计摊销和减值费用 | | | | | | | | | | | | | | | | | | | |
截至2019年1月1日
|
| | | | 2,742 | | | | | | — | | | | | | 2,742 | | |
摊销
|
| | | | 1,295 | | | | | | — | | | | | | 1,295 | | |
处置
|
| | | | (4) | | | | | | — | | | | | | (4) | | |
截至2019年12月31日
|
| | | | 4,033 | | | | | | — | | | | | | 4,033 | | |
账面金额 | | | | | | | | | | | | | | | | | | | |
截至2018年1月1日
|
| | | | 1,858 | | | | | | 235 | | | | | | 2,093 | | |
截至2018年12月31日
|
| | | | 5,975 | | | | | | 238 | | | | | | 6,213 | | |
截至2019年12月31日
|
| | | | 5,416 | | | | | | 282 | | | | | | 5,698 | | |
(千欧元)
|
| |
建筑物
|
| |
技术
设备 和机器 |
| |
其他
设备, 家具 和灯具 |
| |
资产
下的 施工 |
| |
合计
|
| |||||||||||||||
采购成本 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
截至2018年1月1日
|
| | | | 5,398 | | | | | | 12,230 | | | | | | 4,665 | | | | | | 27,103 | | | | | | 49,397 | | |
添加
|
| | | | 490 | | | | | | 953 | | | | | | 719 | | | | | | 7,244 | | | | | | 9,406 | | |
处置
|
| | | | — | | | | | | (150) | | | | | | (157) | | | | | | — | | | | | | (307) | | |
重新分类
|
| | | | — | | | | | | 1,303 | | | | | | 19 | | | | | | (1,323) | | | | | | — | | |
货币换算
|
| | | | — | | | | | | — | | | | | | — | | | | | | 1 | | | | | | 1 | | |
截至2018年12月31日
|
| | | | 5,888 | | | | | | 14,336 | | | | | | 5,247 | | | | | | 33,025 | | | | | | 58,497 | | |
累计折旧和减值费用 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
截至2018年1月1日
|
| | | | 1,337 | | | | | | 4,610 | | | | | | 2,654 | | | | | | 7,120 | | | | | | 15,721 | | |
折旧
|
| | | | 371 | | | | | | 1,299 | | | | | | 890 | | | | | | — | | | | | | 2,559 | | |
处置
|
| | | | — | | | | | | (99) | | | | | | (157) | | | | | | — | | | | | | (255) | | |
截至2018年12月31日
|
| | | | 1,708 | | | | | | 5,810 | | | | | | 3,387 | | | | | | 7,120 | | | | | | 18,025 | | |
|
(千欧元)
|
| |
建筑物
|
| |
技术
设备 和机器 |
| |
其他
设备, 家具 和灯具 |
| |
资产
下的 施工 |
| |
合计
|
| |||||||||||||||
采购成本 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
截至2019年1月1日
|
| | | | 5,888 | | | | | | 14,336 | | | | | | 5,247 | | | | | | 33,025 | | | | | | 58,497 | | |
添加
|
| | | | 854 | | | | | | 2,152 | | | | | | 712 | | | | | | 7,435 | | | | | | 11,152 | | |
处置
|
| | | | (65) | | | | | | (319) | | | | | | (248) | | | | | | — | | | | | | (632) | | |
重新分类
|
| | | | 167 | | | | | | 883 | | | | | | 187 | | | | | | (1,237) | | | | | | — | | |
货币换算
|
| | | | — | | | | | | — | | | | | | 3 | | | | | | 4 | | | | | | 6 | | |
截至2019年12月31日
|
| | | | 6,844 | | | | | | 17,051 | | | | | | 5,902 | | | | | | 39,226 | | | | | | 69,023 | | |
累计折旧和减值费用 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
截至2019年1月1日
|
| | | | 1,708 | | | | | | 5,810 | | | | | | 3,388 | | | | | | 7,120 | | | | | | 18,026 | | |
折旧
|
| | | | 779 | | | | | | 1,637 | | | | | | 899 | | | | | | — | | | | | | 3,315 | | |
处置
|
| | | | (37) | | | | | | (190) | | | | | | (164) | | | | | | — | | | | | | (392) | | |
货币换算
|
| | | | — | | | | | | — | | | | | | 1 | | | | | | — | | | | | | 1 | | |
截至2019年12月31日
|
| | | | 2,449 | | | | | | 7,257 | | | | | | 4,123 | | | | | | 7,120 | | | | | | 20,949 | | |
账面金额 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
截至2018年1月1日
|
| | | | 4,061 | | | | | | 7,621 | | | | | | 2,011 | | | | | | 19,982 | | | | | | 33,675 | | |
截至2018年12月31日
|
| | | | 4,181 | | | | | | 8,526 | | | | | | 1,860 | | | | | | 25,904 | | | | | | 40,472 | | |
截至2019年12月31日
|
| | | | 4,395 | | | | | | 9,795 | | | | | | 1,779 | | | | | | 32,105 | | | | | | 48,075 | | |
| | |
2018
|
| |
2019
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
原材料
|
| | | | 2,742 | | | | | | 6,177 | | |
成品
|
| | | | — | | | | | | 14 | | |
其他
|
| | | | 209 | | | | | | 6 | | |
合计
|
| | | | 2,951 | | | | | | 6,197 | | |
| | |
2018
|
| |
2019
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
短期投资
|
| | | | 39,024 | | | | | | 430 | | |
其他
|
| | | | 229 | | | | | | 1,028 | | |
合计 | | | | | 39,253 | | | | | | 1,458 | | |
|
系列
|
| |
个共享
|
| |||
A
|
| | | | 3,114,021 | | |
B
|
| | | | 91,649,616 | | |
C
|
| | | | 1,929,628 | | |
合计
|
| | | | 96,693,265 | | |
| | |
2018
|
| |
2019
|
| ||||||
期初未完成
|
| | | | 7,972,425 | | | | | | 6,640,449 | | |
期间发放的
|
| | | | — | | | | | | 665,389 | | |
在
期间过期
|
| | | | (1,331,976) | | | | | | — | | |
期末未清偿
|
| | | | 6,640,449 | | | | | | 7,305,838 | | |
其归属(和费用)
|
| | | | 6,640,449 | | | | | | 7,305,838 | | |
| | |
2018
|
| |
2019
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
研发费用
|
| | | | 4,229 | | | | | | — | | |
一般和行政费用
|
| | | | 21 | | | | | | (6,074) | | |
合计 | | | | | 4,250 | | | | | | (6,074) | | |
|
加权平均公允价值
|
| | | | EUR3.80 | | |
|
加权平均股价
|
| | | | EUR9.19 | | |
|
行权价(6.21美元)
|
| | | | EUR5.64 | | |
|
预期波动率(%)
|
| | | | 50.0% | | |
|
预期寿命(年)
|
| | | | 1.16 | | |
|
无风险利率(%)
|
| | | | 1.77% | | |
|
期初未完成
|
| | | | — | | |
|
期间发放的
|
| | | | 745,236 | | |
|
期末未清偿
|
| | | | 745,236 | | |
|
其归属
|
| | | | 175,397 | | |
|
已支出
|
| | | | 284,387 | | |
| | |
2019
|
| |||
| | |
欧元k
|
| |||
研发费用
|
| | | | (258) | | |
销售和分销费用
|
| | | | (743) | | |
一般和行政费用
|
| | | | (79) | | |
合计 | | | | | (1,080) | | |
|
加权平均公允价值
|
| | | | EUR3.87 | | |
|
加权平均股价
|
| | | | EUR9.19 | | |
|
行权价(8.27美元)
|
| | | | EUR7.50 | | |
|
预期波动率(%)
|
| | | | 50.0% | | |
|
预期寿命(年)
|
| | | | 4.77 | | |
|
无风险利率(%)
|
| | | | 1.71% | | |
|
期初未完成
|
| | | | — | | |
|
期间发放的
|
| | | | 3,866,309 | | |
|
期末未清偿
|
| | | | 3,866,309 | | |
|
其归属
|
| | | | 2,819,120 | | |
|
已支出
|
| | | | 3,207,042 | | |
| | |
2019
|
| |||
| | |
欧元k
|
| |||
一般和行政费用
|
| | | | (12,409) | | |
合计 | | | | | (12,409) | | |
| | |
2018
|
| |
2019
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
贸易应付款
|
| | | | (9,029) | | | | | | (5,331) | | |
应付许可费
|
| | | | (501) | | | | | | (537) | | |
其他负债
|
| | | | (1,383) | | | | | | (607) | | |
合计 | | | | | (10,913) | | | | | | (6,475) | | |
| | |
2018
|
| |
2019
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
累计奖金
|
| | | | 1,903 | | | | | | 2,477 | | |
累计休假
|
| | | | 682 | | | | | | 780 | | |
未付发票
|
| | | | 6,812 | | | | | | 3,478 | | |
专业费
|
| | | | 292 | | | | | | 578 | | |
来自政府机构和类似机构的赠款
|
| | | | 1,186 | | | | | | 4,148 | | |
其他
|
| | | | 271 | | | | | | 554 | | |
合计 | | | | | 11,146 | | | | | | 12,015 | | |
| | |
2018
|
| |
2019
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
税前亏损
|
| | | | (71,131) | | | | | | (100,125) | | |
预期税收优惠(基于2019年和2018年29.13%的法定税率)
|
| | | | 20,744 | | | | | | 29,162 | | |
对上一年度当期所得税的调整
|
| | | | 42 | | | | | | — | | |
集团税率和地方税率差异的影响
|
| | | | 10 | | | | | | 8 | | |
未确认税损结转的影响
|
| | | | (22,428) | | | | | | (22,836) | | |
无法识别DTA/DTL造成的影响
|
| | | | — | | | | | | — | | |
首次确认税损结转
|
| | | | 430 | | | | | | — | | |
税收方面不可抵扣的费用
|
| | | | | | | | | | | | |
不可抵扣的股份支付对−的影响
|
| | | | 1,209 | | | | | | (5,698) | | |
当地贸易税(加计/扣减)产生的−效应
|
| | | | (65) | | | | | | (191) | | |
−其他不可抵扣费用
|
| | | | (53) | | | | | | (78) | | |
其他效果
|
| | | | — | | | | | | (114) | | |
有效税收优惠/(费用)
|
| | | | (110) | | | | | | 252 | | |
税损结转
|
| |
2018
|
| |
2019
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
企业所得税未使用税损
|
| | | | 330,753 | | | | | | 407,434 | | |
贸易税未使用税损
|
| | | | 329,210 | | | | | | 405,123 | | |
2019
|
| |
少于
3个半月 欧元 |
| |
3至12个月
欧元 |
| |
1至5年
欧元 |
| |
>5年
欧元 |
| |
合计
欧元 |
| |||||||||||||||
可转换贷款
|
| | | | — | | | | | | — | | | | | | (83,940) | | | | | | — | | | | | | (83,940) | | |
租赁负债(附注2)
|
| | | | (732) | | | | | | (1,985) | | | | | | (9,192) | | | | | | (5,086) | | | | | | (16,995) | | |
其他负债
|
| | | | — | | | | | | (12,015) | | | | | | (362) | | | | | | (167) | | | | | | (12,544) | | |
贸易和其他应付款
|
| | | | (5,938) | | | | | | (537) | | | | | | — | | | | | | — | | | | | | (6,475) | | |
合计 | | | | | (6,670) | | | | | | (14,537) | | | | | | (93,494) | | | | | | (5,253) | | | | | | (119,954) | | |
|
2018
|
| |
少于
3个半月 欧元 |
| |
3至12个月
欧元 |
| |
1至5年
欧元 |
| |
>5年
欧元 |
| |
总计欧元
|
| |||||||||||||||
融资租赁负债
|
| | | | (29) | | | | | | (48) | | | | | | — | | | | | | — | | | | | | (77) | | |
其他负债
|
| | | | — | | | | | | (11,146) | | | | | | (688) | | | | | | (175) | | | | | | (12,009) | | |
贸易和其他应付款
|
| | | | (10,378) | | | | | | (535) | | | | | | — | | | | | | — | | | | | | (10,913) | | |
合计 | | | | | (10,407) | | | | | | (11,729) | | | | | | (688) | | | | | | (175) | | | | | | (22,999) | | |
2018
|
| |
少于
3个半月 欧元 |
| |
3至12个月
欧元 |
| |
1至5年
欧元 |
| |
>5年
欧元 |
| |
总计欧元
|
| |||||||||||||||
经营租赁承诺额
|
| | | | — | | | | | | (84) | | | | | | (91) | | | | | | — | | | | | | (175) | | |
租赁协议
|
| | | | (683) | | | | | | (2,576) | | | | | | (21,160) | | | | | | (23,589) | | | | | | (48,008) | | |
合计 | | | | | (683) | | | | | | (2,660) | | | | | | (21,251) | | | | | | (23,589) | | | | | | (48,183) | | |
| | |
2019
(千) |
| |||
现金和现金等价物
|
| |
22,608欧元
|
| |
25,398美元
|
|
贸易和其他应收账款
|
| |
9458欧元
|
| |
10,585美元
|
|
其他应收账款
|
| |
105欧元
|
| |
93英镑
|
|
| | |
84欧元
|
| |
92瑞士法郎
|
|
| | |
81欧元
|
| |
91美元
|
|
外币货币资产
|
| |
32,336欧元
|
| | | |
贸易和其他应付款
|
| |
505欧元
|
| |
567美元
|
|
| | |
219欧元
|
| |
186英镑
|
|
| | |
10欧元
|
| |
11瑞士法郎
|
|
外币货币负债
|
| |
734欧元
|
| | | |
| | |
2018
(千) |
| |||
现金和现金等价物
|
| |
16941欧元
|
| |
19398美元
|
|
贸易和其他应收账款
|
| |
2059欧元
|
| |
3374美元
|
|
外币货币资产
|
| |
1.9万欧元
|
| |
22,772美元
|
|
贸易和其他应付款
|
| |
8002欧元
|
| |
9162美元
|
|
| | |
132欧元
|
| |
118英镑
|
|
| | |
46欧元
|
| |
51瑞士法郎
|
|
外币货币负债
|
| |
8180欧元
|
| | | |
| 2018年(1欧元=1.1450美元) | | | 2019年(1欧元=1.1234美元) | |
| 10,544k欧元,13,090k美元 | | | 30,656k欧元,34,400k美元 | |
千欧元
|
| |
1月1日
2019 |
| |
现金
流程 |
| |
重新分类
|
| |
新
租约 |
| |
累计
利息 |
| |
外来
交换 移动 |
| |
12月31日
2019 |
| |||||||||||||||||||||
可转换贷款
|
| | | | — | | | | | | 69,889 | | | | | | (7,604) | | | | | | — | | | | | | 2,733 | | | | | | — | | | | | | 65,018 | | |
租赁负债
|
| | | | 15,810 | | | | | | (1,910) | | | | | | — | | | | | | 153 | | | | | | — | | | | | | 77 | | | | | | 14,130 | | |
融资负债总额
活动 |
| | | | 15,810 | | | | | | 67,979 | | | | | | (7,604) | | | | | | 153 | | | | | | 2,733 | | | | | | 77 | | | | | | 79,148 | | |
千欧元
|
| |
1月1日
2018 |
| |
更改自
融资 现金流 |
| |
12月31日
2018 |
| |||||||||
租赁负债
|
| | | | 188 | | | | | | (112) | | | | | | 77 | | |
融资活动的总负债
|
| | | | 188 | | | | | | (112) | | | | | | 77 | | |
2019年密钥管理薪酬
|
| |
管理
板 |
| |
监管
板 |
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
短期效益
|
| | | | 3,166 | | | | | | 521 | | |
股份支付
|
| | | | 18,483 | | | | | | — | | |
合计 | | | | | 21,649 | | | | | | 521 | | |
2018年密钥管理薪酬
|
| |
管理
板 |
| |
监管
板 |
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
短期效益
|
| | | | 2,195 | | | | | | 343 | | |
合计 | | | | | 2,195 | | | | | | 343 | | |